Biochemical Assessment of Renal Function: MCQ

The renal system covers the glomerular function, tubular function, acid-base homeostasis, biochemical assessment, and clinical correlations. The glomerulus is mainly involved in the filtration of the blood for the excretion of waste products while retaining most of the proteins. The renal tubules function in secretion, reabsorption, and excretion of electrolytes, ions, organic acids, urea. The renal tubules help regulate osmolality, volume, and pH of the blood. This chapter includes the biochemical test and interpretation for diagnosis and monitoring of renal diseases.

Multiple Choice Question on 
Biochemical Assessment of Kidney

1) The clearance test of a substance such as creatinine is used for the estimation of glomerular filtration rate and an index of renal function. Which of the following are the characteristics of substance ideal for estimation of GFR?
a) Stable plasma concentration that is easily measured
b) Freely filtered into Bowman's capsule
c) Not reabsorbed, secreted or metabolized in the kidney
d) All of the above

2) The figure below represents the clearance of four different substances (Glucose, Creatinine, Inulin, and Para amino hippuric acid). Identify the clearance of the chart based on its reabsorption and secretion in the kidney.

3) Which of the following is the gold standard substance for the clearance test used for estimation of GFR?
a) Para-amino-hippuric acid
b) Creatinine
c) Inulin
d) Glucose

4) Select the correct Creatinine Clearance from the following laboratory parameters
a) 100 mL/min
b) 120 mL/min
c) 140 mL/min
d) 160 mL/min
(Link for Calculations)

Answer
1- d) All of the above
2- Answers: A- Para amino hippuric acid, B- Creatinine, C- Inulin, D-Glucose
3-c) Inulin
4)-b

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