Multiple Choice Questions (MCQs) on Acute Rheumatic Fever and Group A Streptococcus with Explanations: Medical microbiology
Multiple Choice Questions (MCQs) on Acute Rheumatic Fever and Group A Streptococcus with Explanations: Question 1: Acute Rheumatic Fever (ARF) is primarily caused by which bacterial species? a) Staphylococcus aureus b) Streptococcus pneumoniae c) Streptococcus agalactiae d) Streptococcus pyogenes (Group A Streptococcus) Answer: d) Streptococcus pyogenes (Group A Streptococcus) Explanation: ARF is primarily caused by Group A Streptococcus (S. pyogenes), particularly following untreated or inadequately treated streptococcal infections. Question 2: Which virulence factor of Streptococcus pyogenes plays a key role in the development of Acute Rheumatic Fever? a) Capsule b) Lipopolysaccharide (LPS) c) M protein d) Teichoic acid Answer: c) M protein Explanation: The M protein on the surface of Streptococcus pyogenes plays a crucial role in molecular mimicry, triggering the autoimmune response responsible for Acute Rheumatic Fever. Question 3: Molecular mimicry in Acute Rheumatic Fever refers ...