TOPAMAX (topiramate), FDA Approved Drug For the Treatment of Epilepsy Topiramate is a sulfamate-substituted monosaccharide. TOPAMAX (topiramate). Topiramate is designated chemically as 2,3:4,5 Di-O-isopropylidene-beta-D-fructopyranose sulfamate. TOPAMAX (topiramate capsules) Sprinkle Capsules are available as 15 mg and 25 mg sprinkle capsules for oral administration as whole capsules or opened and sprinkled onto soft food. Indication of TOPAMAX TOPAMAX (topiramate) is indicated for: Monotherapy epilepsy: Initial monotherapy in patients with & above 2 years of age with partial-onset or primary generalized tonic-clonic seizures Adjunctive therapy epilepsy: Adjunctive therapy for adults and pediatric patients (2 to 16 years of age) with partial-onset seizures or primary generalized tonic-clonic seizures, and in patients with and above 2 years of age with seizures associated with Lennox-Gastaut syndrome (LGS) ( Migraine: Treatment for adults and adolescen...