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Showing posts with the label heparin and warfarin

Lecture Notes on Anticoagulants (Heparin & Warfarin)

Overview of the Topics Anticoagulant Drugs Thrombolytic Drugs (Click Here) Antiplatelet Drugs (Click Here) Multiple Choice Practice Questions (Click Here) Anticoagulant drugs:  - Drugs that inhibit the development and enlargement of clots by action on the coagulation phase.  - Do not lyse clots or affect the fibrinolytic pathways  Clinical Indication for Anticoagulant therapy - Deep Vein Thrombosis - Arterial Embolism - Arterial Fibrillation  - Unstable angina and myocardial infarction Heparin (Intravenous or subcutaneous administration) - Heparin is a sulfated acidic mucopolysaccharide that is widely distributed in the body - Two types of heparin are used clinically - Standard Unfractionated Heparin - Low Molecular Weight Heparin Standard Unfractionated Heparin - Heparin (heparin sodium) is a mixture of highly electronegative acidic mucopolysaccharides that contain numerous N- and O-sulfate linkages.  - The unfractionated preparation is extracted f...