PBL case objective a)Differential Diagnosis of Jaundice b)Biochemical basis for the diagnosis of acute liver disease c) Biochemical basis for the diagnosis of obstructive jaundice Clinical case 1: A 52-year-old male patient arrived at the medical facility with complaints of nausea, vomiting, abdominal pain, and yellowing of the skin (icteric jaundice) that had persisted for one week. Upon conducting a physical examination, the patient was found to have stable vital signs, and there were no signs of hepatic encephalopathy (a condition affecting brain function due to liver disease). The patient exhibited yellowing of the sclera (the white part of the eyes) and tenderness in the right upper quadrant of the abdomen when touched. The laboratory investigation results are presented below. Total serum Bilirubin - 15.4 mg/dL Direct bilirubun-11.5 mg/dl Aspartate transaminase- 720 U/L Alanine transaminase - 1625 U/L Alkaline Phosphatase- 211 U/L Total Protein- 7.3 g/dl...