BIOCHEMISTRY, BIOMEDICINE & PHARMACEUTICS

Overview of the Topics Anticoagulant Drugs (Click Here) Thrombolytic Drugs (Click Here) Antiplatelet Drugs (Click Here) Multiple Choice Practice Questions  Anticoagulants: 1) Identify the class of drug prescribed for acute management of deep vein thrombosis : a) Anticoagulants, eg. warfarin b) Thrombolytics, eg. tPA c) Antiplatelets, eg. Aspirin d) All of the above 2) Identify the class of drug prescribed for the long term management of deep vein thrombosis : a) Anticoagulants eg. warfarin b) Thrombolytics eg. tPA c) Antiplatelets eg Aspirin d) All of the above 3) Standard unfractionated Heparin is now replaced by the low molecular weight heparin. Standard unfractionated heparin is still the preferred anticoagulant in deep vein thrombotic patients with a coincidence of ............................................? a) Liver abnormalities b) Renal Dysfunction c) Cardiovascular disorder d) Myocardial Infarction  4) Which of the following is the mechanism of action of heparin...

Overview of the Topics Anticoagulant Drugs Thrombolytic Drugs (Click Here) Antiplatelet Drugs (Click Here) Multiple Choice Practice Questions (Click Here) Anticoagulant drugs:  - Drugs that inhibit the development and enlargement of clots by action on the coagulation phase.  - Do not lyse clots or affect the fibrinolytic pathways  Clinical Indication for Anticoagulant therapy - Deep Vein Thrombosis - Arterial Embolism - Arterial Fibrillation  - Unstable angina and myocardial infarction Heparin (Intravenous or subcutaneous administration) - Heparin is a sulfated acidic mucopolysaccharide that is widely distributed in the body - Two types of heparin are used clinically - Standard Unfractionated Heparin - Low Molecular Weight Heparin Standard Unfractionated Heparin - Heparin (heparin sodium) is a mixture of highly electronegative acidic mucopolysaccharides that contain numerous N- and O-sulfate linkages.  - The unfractionated preparation is extracted f...