Monkeypox, Poxvirus - Medical microbiology (MCQ)

1)The 2022 outbreak of monkeypox virus infection first occurred in Nigeria.
What are the possible routes of transmission of the virus to humans?
Select all the correct answers:
a) Humans to humans
b) Animals to humans
c) Humans to animals
d) Animals to animals

2) Monkeypox infection has been declared a public health emergency in 2022 by the World health organization due to the worldwide spread of the virus.
According to health agencies in the USA which of the following age group are the most affected and are at higher risk?
a)Children 5 to 10 years old
b)Males 18 years and above     
d)Pregnant women

3)Which of the following symptoms are the general symptoms related to monkeypox infection?
a) High fever, raised skin lesions, swollen lymph nodes       
b) High fever, diarrhea, and vomiting
c) High fever, flat skin lesions, vomiting
d) High fever, seizures, and loss of appetite

4) Smallpox and monkeypox viruses come under the same genus of viruses known as orthopoxvirus.
When was the monkeypox virus first isolated and identified?
a) 1938
b) 2022
c) 1958    

5) Monkeypox virus is most prevalent in the African continent and the first case in the USA was reported in 2003. 
Which of the following was identified as the source for the transmission of the virus during that outbreak?
a) Ticks      
b) Birds
c) Contaminated water and food
d) Rodents

6) Human to human monkeypox virus transmission can occur by which of the following routes?
Select all the correct answers:
a) Respiratory droplets        
b) Exposure to skin rashes     
c) Mosquito bites
d) Overuse of drugs

7) One of the common symptoms of Monkeypox infection includes skin blisters or nodules that look like pearls and is widely spread throughout the body.
Which of the following is the most correct time period for the rashes to get reduced?
a) 2- 5 days
b) 2- 3 weeks     
c) 1 week
d) 3- 5 weeks

8) All of the following are the general characteristics of the monkeypox virus, Except?
a) It is a double-stranded DNA virus
b) The infection by the virus is a zoonotic infection
c) Human transmission occurs only through close contact with infected monkeys     
d) The smallpox vaccine is effective against the monkeypox virus

9) Which of the following antiviral drug regimen has been found to be effective and was approved by the FDA in 2018 for the monkeypox virus?
a) Remdesivir for 10 days
b) Tamiflu for 5 weeks
c) Brincidofoir for 4 weeks
d) Ticovarimat for 2 weeks    

10) Which of the following is the most common specimen collected for the correct diagnosis of the monkeypox virus infection?
a) Lesion swab specimen    
b) Sputum specimen
c) Blood specimen
d) Urine specimen

Multiple choice answers:
1. a) Humans to humans, b) Animals to humans, c) Humans to animals, and d) animals to animals
2. b)Males 18 years and above  
3. a) High fever, raised skin lesions, swollen lymph nodes   
4. c)1958
5. d)Rodents
6. a) Respiratory droplets, and b) Exposure to skin rashes     
7. b) 2-3 weeks
8. c) Human transmission occurs only through close contact with infected monkeys  
9. d) Ticovarimat for 2 weeks  
10. a) Lesion swab specimen