Medical Microbiology: MCQ on Rickettsia & Coxiella

Multiple Choice Questions on Rickettsia & Coxiella

1) What are the different types of Rickettsial infections? Select all the correct answers from all the options given below
a) Epidemic typhus
b) Scrub typhus group
c) Yellow fever
d) Rocky mountain spotted fever

2) All the statements given below are correct about epidemic typhus, Except?
a) It is transmitted by louse to humans
b) People above 40 years of age are most affected
c) Fever lasts for about two weeks
d) It is caused by the pathogen Rickettsia typhi

3) Which of the following Rickettsia spp causes Rickettsialpox in humans transferred from the bites of mites developing a mild fever and rashes resembling caused by varicella?
a) Rickettsia rickettsi
b) Rickettsia akari
c) Rickettsia prowazekii
d) Rickettsia australis

4) Which of the following statements is NOT correct about the characteristics of Rocky Mountain spotted fever?
a) It is caused by Rickettsia rickettsii
b) It is mostly found in the eastern and southeastern region of United States
c) Fever and Skin rashes develop within 6 hours of the ticks' bite
d) Ticks are the primary vectors

5) All of the statements given below are correct about the Ehrlichiosis infections in human, EXCEPT?
a) Ehrlichia chaffeensis is the causative organism
b) Ticks are the vectors that transmit Ehrlichiosis infection
c) The infection represents an Intracellular inclusion called morulae
d) The drug of choice is penicillin

6) Which of the following bacterial zoonotic diseases resembling the symptoms of influenza and pneumonia is transferred to humans through goats, sheep, and other cattle?
a) Rocky mountain fever
b) Q fever
c) Dengue fever
d) Yellow fever

7) ….................... causes endemic typhus or murine typhus which is transmitted to humans primarily through rats and cats' fleas.
a) Rickettsia prowazekii
b) Rickettsia rickettsiae
c) Coxiella burnetii
d) Rickettsia typhi

8) What is the most widely used serological test for the diagnosis of the Rickettsia rickettsiae from skin biopsy?
a) Complement fixation test
b) Immunofluorescence technique
c) Schick skin test
d) Agglutination test

9) What is the drug regimen used in the treatment of chronic Q fever?
a) Combination therapy with doxycycline and hydroxychloroquine for up to 18 months
b) Doxycycline for 18 months
c) Combination therapy with penicillin and fluoroquinolones for 12 months
d) Antibiotics do not work in this phase of illness

10) Which of the following statements is mostly correct about the antigenic forms of Coxiella burnetii?
a) The antigens exist in two phases 1 and 2 of which phase one is a virulent form
b) The antigens are less pathogenic when grown in laboratory animals
c) Both a and b
d) None of the above


11) Which of the following diseases is NOT a tick-borne disease?
a) Epidemic typhus
b) Rocky mounted spotted fever
c) Tularemia
d) Ehrlichiosis

12) All of the following are the general features, signs, and symptoms of the Scrub typhus disease caused by Rickettsia spp, EXCEPT?
a) An Eschar ulcer appears at the site of the mite bite
b) Respiratory infections are frequent
c) Lymphadenopathy is common
d) The causative agent is Rickettsia australis

13) .......................also called recrudescent typhus, it is a late relapse of epidemic typhus showing reoccurrence of symptoms similar to the previous infection and can be transmitted from one individual to others.
a) Rickettsialpox
b) Scrub typhus
c) Brill-Zinsser disease
d) Murine typhus

14) Which of the following are the reservoirs of the flea causing endemic typhus?
a) Rats
b) Dogs
c) Ticks
d) Mites

15) Which of the following is NOT the proper preventive method to control rickettsial infections?
a) Use of insecticides to control vectors and reservoirs
b) Elimination of rats and mites
c) Proper hygiene and cleanliness to eliminate lice and fleas
d) Use of sulfonamides for the treatment of epidemic and endemic typhus infections


Multiple Choice Answers Review
1-a) Epidemic typhus & b) Scrub typhus group
2-d) It is caused by the pathogen Rickettsia typhi
3- b) Rickettsia akari
4-c) Fever and Skin rashes develop within 6 hours of the ticks' bite 
5-d) The drug of choice is penicillin
6-b) Q fever
7-d) Rickettsia typhi
8-b) Immunofluorescence technique
9-a) Combination therapy with doxycycline and hydroxychloroquine for up to 18 months
10-b) The antigens are less pathogenic when grown in laboratory animals
11-b) Rocky mounted
12-d) The causative agent is Rickettsia australis
13-c) Brill-Zinsser disease
14-a) Rats
15-d) Use of sulfonamides for the treatment of epidemic and endemic typhus infections

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