MCQ on Inheritance of Genetic Disorders (Dominant, Recessive and X-Linked): Medical Genetics, Biochemistry

Lecture Notes and Multiple Choice Question on Inheritance Pattern of Genetic Disorders

Multiple Choice Questions on Inheritance Pattern of Genetic Disorders

1) Which of the following statement is true regarding the Mendelian Theory of Inheritance?

a) The genotype ratio for the second generation is 1:2:1

b) The phenotype ratio for the second generation is 3:1

c) The inheritance pattern assume one gene-one protein phenomenon

d) All of the above

2) Which of the following statements are true regarding the dominant traits?

a) One dominant allele (heterozygotes) is sufficient to show the dominant trait

b) Both dominant alleles (homozygous) are required to show the dominant trail

c) Heterozygotes (individuals with one allele) are generally carriers

d) None of the Above

3) Which of the following statements are true regarding the recessive traits?

a) One recessive allele (heterozygotes) is sufficient to show the phenotypic trait

b) Both recessive alleles (homozygous) are required to show the phenotypic trail

c) Heterozygotes (individuals with one allele) are generally carriers.

d) Option a & b

e) Option a & c

4) Identify the correct statement regarding autosomal dominant disorders.

a) At least one parent with the heterozygous mutation is sufficient for showing the phenotype in progeny

b) The affected individuals are always homozygous for the mutant allele

c) Often heterozygotes (individuals with one allele) are generally carriers.

d) None of the above

5) Identify the correct statement regarding autosomal recessive disorders.

a) At least one parent with the heterozygous mutation is sufficient for showing the phenotype in progeny

b) The affected individuals are always homozygous for the mutant allele

c) Often heterozygotes (individuals with one allele) are generally carriers.

d) None of the above

6) Which of the following statement is false regarding the X-linked recessive inherited disorders?

a) The daughters from affected fathers are generally carriers

b) The mutant allele in sons are inherited from the mother

c) The mutant allele in sons are inherited from the father

d) None of the above

7) Which of the following statement is true regarding the X-linked dominant inherited disorders?

a) The daughters from affected fathers are generally carriers

b) The mutant allele in affected sons are inherited from the mother

c) The mutant allele in affected sons are inherited from the father

d) None of the above

8) Identify the pattern of inheritance from the linkage below

a) Autosomal Dominant

b) Autosomal Recessive

c) X-linked Recessive

d) X-linked Dominant

9) Identify the pattern of inheritance from the linkage below

a) Autosomal Dominant

b) Autosomal Recessive

c) X-linked Recessive

d) X-linked Dominant

10) The following statements are true regarding the inheritance of disorders of mitochondrial DNA

a) The disorders of mitochondrial DNA are inherited from males

b) The disorders of mitochondrial DNA are inherited from females

c) The penetrance of the disease is tightly variable

d) None of the above

11) Which of the following genetic disorder is inherited in an autosomal recessive manner?

a) Sickle cell anemia

b) Achondroplasia

c) Hemophilia

d) Leber's Hereditary Optic Neuropathy

12) Achondroplasia is the hyperactive mutation of the FGFR3 receptor, which of the following is the possible pattern of inheritance

a) X-linked Dominant

b) Autosomal Recessive

c) X-linked Recessive

d)Autosomal Dominant

Answers :

1-d) All of the above

2-a) One dominant allele (heterozygotes) is sufficient to show the dominant trait

3- e) Option a & c

4-a) At least one parent with the heterozygous mutation is sufficient for showing the phenotype in progeny

5-b) The affected individuals are always homozygous for the mutant allele

6-c) The mutant allele in sons are inherited from the father

7-b) The mutant allele in affected sons are inherited from the mother

8-b) Autosomal Recessive

9-c) X-linked Recessive

10- Option b & c

11-a) Sickle cell anemia

12-d) Autosomal Dominant

Carbohydrate Metabolism: MCQs and answers on Glycolysis & Gluconeogenesis

MCQ on Glycolysis & Gluconeogenesis 1) Which of the following enzyme is not involved in galactose metabolism? a) Glucokinase b) Galactokinase c) Galactose-1-Phosphate Uridyl transferase d) UDP-Galactose 4- epimerase 2) Which of the following enzyme is defective in galactosemia (type I) - a fatal genetic disorder in infants? a) Glucokinase b) Galactokinase c) Galactose-1-Phosphate Uridyl transferase d) UDP-Galactose 4- epimerase 3) In the liver, the accumulation of which of the following metabolite attenuates the inhibitory of ATP on phosphofructokinase? a) Glucose-6-Phosphate b) Citrate c) Fructose-1,6-Bisphosphate d) Fructose-2,6-Bisphosphate 4) Mutation in which of the following enzymes leads to a glycogen storage disease known as "Tarui’s disease"? a) Glucokinase b) Phosphofructokinase c) Phosphoglucomutase d) Pyruvate Kinase 5) E...

MCQs and Answers on cultivation (culture/incubation), Isolation and Identification of microorganisms: Medical Microbiology

40 plus questions - Multiple Choice Questions on Classification, Culture, and Identification of the microorganisms 1. Which of the following microorganism has the cocci cell shapes and sizes arranged usually in tetrad structures? a) Streptococcus pneumoniae b) Staphylococcus aureus c) Chlamydia trachomatis d) Neisseria meningitidis 2. What are the different growth morphology and cell structures used for the classification of fungi? Select all the correct answers: a) Yeast b) Mold c) Mycelia d) Protozoa 3. Which of the following media is formulated with additional nutrients to support the growth of fastidious or nutritionally demanding bacteria that may not grow well on basic media? a) Differential media b) Enriched media c) Nutrient agar (media) d) Selective media 4. Which of the following metabolic characteristic is a distinguishing characteristic and identification of colonies of E. coli ? a) Hydrogen sulfide formation b) Indole Formation c) Lactose fe...

Multiple Choice Questions (MCQs) on Diabetes Mellitus: Pathogenesis, Diagnosis and Treatment

MCQs on Diabetes mellitus 1) Diabetes mellitus is a disorder characterized by hyperglycemia. Which of the following is not the common characteristic features of type 2 diabetes mellitus ? a) Impaired insulin secretion b) Increased Insulin resistance c) Diabetic ketoacidosis d) Excessive hepatic glucose production 2) Which of the following are the characteristic features of type 1 diabetes mellitus? a) Type 1 diabetes is caused by an absolute deficiency of insulin. b) Type 1 diabetes is associated with the autoimmune destruction of beta cells. c) Patients with uncontrolled type 1 diabetes present with diabetic ketoacidosis d) All of the above 3) Which of the following serum measurements are not used for the diagnosis of diabetes mellitus? a) Fasting blood glucose d) Postprandial blood glucose c) Insulin ...

BIOCHEMISTRY, BIOMEDICINE & PHARMACEUTICS

Search This Blog