MCQs on Infectious diseases
Bacteria?
Virus?
Fungi?
Parasites?
a)Diarrheal diseases
b)HIV/AIDS
c)Respiratory tract infections
d)Tuberculosis
e) Malaria
2. A 56 year old man from a rural part of the Philippines with COPD (chronic inflammatory lung disease) visited the clinic. Symptoms included shortness of breath, abdominal pain, and fever for the last 24 hours, his oxygen saturation level came around 87 which was below the normal range. Pneumonia was suspected, thus a sputum sample and blood sample were taken for the gram staining examination, the results were uncertain.
Further, a wet preparation procedure was done, and under the microscope, worms were detected.
What is the possible diagnosis?
a) Infectious mononucleosis
b) Nocardiosis
c) Strongyloidiasis
d) Sporotrichosis
3) From the above question (2), which of the following can be the most common route/source of transmission to humans?
a) Close contact with soil and farms
b) Person to person through respiratory air droplets
c) Through the bite of ticks and fleas
d) Sexually transmitted infection
4) Which of the following infectious diseases can be preventable through vaccination?
Select all the correct answers:
a) Diptheria
b) Measles
c) Hepatitis B
d) HIV
5) Which of the following parasite is responsible for the disease malaria and is a leading cause of deaths occurring in tropical and subtropical regions?
a) Hepatitis B virus
b) Zika virus
c) Plasmodium falciparum
d) Pneumocystis carinii
6) Which of the following is a major intestinal pathogen and is a leading cause of diarrheal deaths occurring in nations that do not have sufficient safe drinking water?
a) Entamoeba histolytica
b) Vibrio cholera
c) Shigella dysenteriae
d) Yersinia enterocolitica
7) Name the antibiotic that is most effective for the treatment of the typhoid
a) Amphotericin B
b) Rifampicin
c) Retrovir
d) Ciprofloxacin
8) Which of the following viral infection can lead to hemorrhagic fever in the chronic stage of the disease?
a) Dengue
b) Malaria
c) Tuberculosis
d) Polio
9) Which of the following pulmonary infection is one of the leading causes of death among people with HIV?
a) Cystic fibrosis
b) Tuberculosis
c) Nocardiosis
d) Toxoplasmosis
10) Which of the following viruses are the common cause of upper respiratory tract infections?
Select all the correct answers:
a) Rhinovirus
b) Influenza virus
c) Norovirus
d) Coronavirus
a) Tuberculosis
b) Malaria
c) Influenza
d) Lyme disease
12. Which pandemic is caused by the SARS-CoV-2 virus?
a) Spanish flu
b) COVID-19
c) H1N1 influenza
d) Ebola virus disease
13. Which of the following is a preventive measure for reducing the spread of infectious diseases?
a) Regular exercise
b) Taking over-the-counter painkillers
c) Eating a balanced diet
d) Getting vaccinated
14. Which of the following diseases is primarily transmitted through contaminated food and water?
a) Cholera
b) Tuberculosis
c) Zika virus
d) Dengue fever
15. Which of the following is a fungal infection that affects the skin, hair, or nails?
a) Dengue fever
b) Shigellosis
c) Athlete's foot
d) Influenza
16) Max, an office worker with no significant past medical histrory presents to the clinic with symptoms of fever, sore throat, fatigue, and a generalized rash for the past two weeks. He mentions that these symptoms started after a recent sexual encounter with a new partner. He is concerned about the possibility of an STD.
Symptoms began approximately two weeks ago. Symptoms have been persistent that include night sweats, swollen lymph nodes, weight loss. He had unprotected sexual contact with a new partner three weeks ago.
Physical Examination: Appears mildly ill, low-grade fever (38.2°C). Enlarged cervical and axillary lymph nodes. Maculopapular rash on the trunk and arms, normal heart sounds, no murmurs and clear breath sounds bilaterally.
Abdomen is soft, non-tender, no hepatosplenomegaly.
Initial Investigations:
Complete Blood Count (CBC): Mild leukopenia
Comprehensive Metabolic Panel (CMP): Normal
Rapid HIV Test: Positive
Given the positive rapid HIV test and the patient’s high-risk behavior, further confirmatory testing and evaluation are warranted.
Which of the following is the common initial confirmatory screening test in the diagnosis of HIV?
a. Complete Blood Count (CBC)
b. Comprehensive Metabolic Panel (CMP)
c. HIV Viral Load (RNA PCR)
d. Rapid HIV Test
17) CD4 cells are the primary targets for HIV, monitoring CD4 count in HIV-infected individuals is critical for assessing immune function and the progression of the disease.
What is the normal range for CD4 count in a healthy individual?
a. 100-300 cells/mm³
b. 200-400 cells/mm³
c. 500-1,500 cells/mm³
d. 1,000-2,000 cells/mm³
18. What additional test is essential before initiating antiretroviral therapy (ART)?
a. Tuberculosis Screening
b. Hepatitis B and C Serologies
c. HIV Genotype Resistance Testing
d. All of the above
Answers with explanation:
1. a)Diarrheal diseases, b)HIV/AIDS, c)Respiratory tract infections, d)Tuberculosis, and e) Malaria
2.c) Strongyloidiasis, Also known as threadworm infection, is a parasitic disease caused by the nematode (roundworm) called Strongyloides stercoralis. It is primarily found in tropical and subtropical regions, including parts of Africa, Asia, Central and South America, and certain areas in the southern United States.
3. a) Close contact with soil and farms, the infection is usually acquired when people come into contact with contaminated soil or water, such as through barefoot walking, ingestion of contaminated food, or poor hygiene practices.
4. a) Diptheria, b) Measles, and c) Hepatitis B. Currently there is no vaccine available for HIV.
5.c) Plasmodium falciparum is a parasite that causes malaria and is transmitted to humans by mosquitoes bite. Hepatitis B virus and Zika virus are viruses and Pneumocystis carinii is a fungal pathogen.
6. b) Vibrio cholera, is a leading cause of diarrheal deaths that occur in developing and underdeveloped nations.
7. d) Ciprofloxacin, a Flouroquinolone, it is first drug of choice that is safe and effective for the treatment of typhoid.
8. a) Dengue fever is a viral infection transmitted to humans by the bite of mosquitoes.
b) Malaria is caused by parasite that is transmitted to humans by the bite of mosquitoes, c) Tuberculosis
is a bacterial infection and d) Polio virus is viral infection, that can lead to irreversible paralysis.
9. b) Tuberculosis is a major pulmonary infection, a common opportunistic infection in HIV infected individuals.
10. a) Rhinovirus, b) Influenza virus, and d) Coronavirus. c) Norovirus is a contagious virus that causes diarrhea and vomiting, also called stomach flu.
11. c) Influenza, Tuberculosis is a contagious pulmonary bacterial infection, b) Malaria is a parasitic infection and d) Lyme disease is a bacterial (spirochete) infection transmitted by to humans by the bite of ticks.
12. b) COVID-19
13. d) Getting vaccinated
14. a) Cholera
15. c) Athlete's foot is a fungal infection, Dengue fever is viral infection b) Shigellosis is a bacterial infection and d) Influenza is a viral infection.
16. d)Rapid HIV Test
It is a diagnostic tool used to quickly detect the presence of HIV antibodies and/or antigens in a person's blood or oral fluid. This test provides results within 20 to 30 minutes, making it a convenient option for early detection and screening.
17. c) 500-1,500 cells/mm³
CD4 cells is a type of white blood cell, CD4 count is a measure of the number of CD4+ T lymphocytes (CD4 cells) in a cubic millimeter (mm³) of blood.
18. d) All of the above
People living with HIV are at an increased risk of tuberculosis (TB) and hepatitis B (HBV) or hepatitis C (HCV) due to their compromised immune systems. It is important to know a patient’s additional infection because some antiretroviral drugs (e.g., tenofovir and emtricitabine) are active against these infections.
HIV genotype resistance testing identifies mutations in the HIV virus that confer resistance to specific antiretroviral drugs. This test ensures that the prescribed ART regimen will be effective against the patient's particular strain of HIV.
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