MCQ on Bacterial Pathogenesis (Medical Microbiology)

Multiple Choice Question on Bacterial Pathogenesis

1) Which of the following microorganism is the major inhabitant of the human skin?
a) Escherichia coli
b) Staphylococcus epidermidis
c) Staphylococcus aureus
d) Streptococcus pyogenes

2) Select all the medically important bacteria which are frequently isolated as a major pathogen of human infections?
a) Enteric bacteria 
b) Pseudomonas spp
c) Plasmodium spp
d) Staphylococcus spp
e) Mucor spp
f) Mycobacterium spp

3) All of the following pathogens can cause congenital infections that are transmitted from infected mother to baby, Except?
a) Treponema pallidum
b) Zika virus
c) Herpesvirus
d) Clostridium perfringens

4) Which of the following cocci-shaped bacteria usually grow in pairs?
a) Klebsiella spp
b) Neisseria spp
c) Pseudomonas spp
d) Clostridium spp
e) Nocardia spp

5) Which of the following microbe can live only inside the cell (obligate intracellular pathogen)?
a) Salmonella
b) Mycobacterium
c) Rickettsia
d) Vibrio

6) ..................................... is the normal flora of the upper respiratory tract of the human body
a) Lactobacillus spp
b) Staphylococcus spp
c) Vibrio spp
d) None of the above

7) Which of the following bacteria releases an endotoxin that causes muscular paralysis?
a) Clostridium botulism
b) Bacillus cereus
c) Streptococcus pyogenes
d) Salmonella typhi

8) Staphylococcus spp produces which of the following enzyme?
a) Proteases
b) Lipase
c) Hyaluronidase
d) Coagulase

9) Which of the following bacteria is predominantly present in the urogenital flora of a mother and a newborn female infant?
a) Candida albicans
b) Lactobacillus acidophilus
c) Escherichia coli
d) Neisseria gonorrohea

10) All of the following bacteria are the predominant normal flora of human feces, EXCEPT
a) Pseudomonas sps
b) Bacteroides sps
c) Enterococcus sps
d) Bacillus sps

11) Name the pathogen transmitted to humans by the bite of fleas that can cause a serious and deadly infection
a) Salmonella typhi
b) Yersinia pestis
c) Shigella dysenteriae
d) Escherichia coli

12) Some bacteria and fungi need an iron receptors molecule for their growth which is an important virulence factor of bacterial pathogenesis, what is it called?
a) Siderophores
b) Ionophores
c) Siderocytes
d) None of the above

13) Which toxin is produced by Streptococcus pyogenes?
a) Shiga like toxin
b) Alpha toxin
c) Erythrogenic toxin
d) Cyanotoxin

14) Name the bacteria that is a common cause of toxic shock syndrome
a) Staphylococcus epidermidis
b) Staphylococcus aureus
c) Staphylococcus intermedius
d) None of the above

15) Catalase test is the common biochemical test used for the identification of various bacteria. 
Which of the following bacteria does not have this enzyme?
a) Enterobacter
b) Pseudomonas
c) Corynebacterium
d) Streptococci

16) Staphylococcus aureus releases various types of toxins that increase the virulence of the bacteria, Select all the toxins released by S.aureus:
a) Aflatoxin
b) Mycotoxin
c) Leucocidin
d) Enterotoxin

17) Which pathogen is a major cause of dental disease?
a) Staphylococcus epidermidis
b) Streptococcus mutans
c) Staphylococcus aureus
d) Streptococcus agalactiae

18) The microorganism that commonly causes an eye infection is
a) Chlamydia trachomatis
b) Staphylococcus aureus
c) Streptococcus pneumoniae
d) Streptococcus sanguinis

19) The most significant bacteria found in acne is .............................acnes.
a) Staphylococcus
b) Streptococcus
c) Propionibacterium
d) Bacillus

20) Which of the following bacteria is predominantly present as normal flora in urine?
a) Escherichia coli
b) Staphylococcus epidermidis
c) Staphylococcus aureus
d) Streptococcus pyogenes

21) The virulence factors of a bacteria are the important constituents of the bacteria that help in invading the host and initiating the infection. 
Select all the important virulence factors which help in the process of bacterial pathogenesis:
b)Exotoxins and endotoxins
c)Pili/ fimbriae
e) All of the above

22) Name the most possible bacteria associated with the opportunistic infections that occur in patients who have cystic fibrosis
a) Staphylococcus aureus
b) Pseudomonas aeruginosa
c) Chlamydia trachomatis
d) Candida albicans

23) Select all the microorganisms which are commonly transmitted to humans by the vectors such as ticks and fleas.
a) Rickettsia spp
b) Yersinia spp
c) Borrelia spp
d) Bacillus spp

24)Which of the following toxins releasing bacteria are common worldwide human gastroenteritis pathogens?
a) Salmonella typhii
b) Streptococcus pneumoniae
c) Cryptococcus neoformans
d) Clostridium botulinum

25) Name the possible pathogen that can invade the skin and cause tissue damage in humans
a) E.coli
b) Bacillus cereus
c) Clostridium perfringens
d) Proteus mirabilis

Multiple Choice Answer Review
1- b) Staphylococcus epidermidis
2-a), b), d), and f) 
c)Plasmodium is a protozoa, e)Mucor spp is a fungi
3- d) C.perfringens
4-b) Neisseria spp
5-c) Rickettsia spp
6- b) Staphylococcus spp
7-a) Clostridium botulism
8-d) Coagulase
9-b) Lactobacillus acidophilus
10-a) Pseudomonas spp
11-b) Yersinia pestis
12-a) Siderophores
13-b) Alpha toxin
14-b) Staphylococcus aureus
15-d) Streptococci
16-c), and d)
17-b) Streptococcus mutans
18-a) Chlamydia trachomatis
19-c) Propionibacterium
20-a) Escherichia coli
21-f) All of the above
23-a), b), and c)
24-a) and d)
25- c)Clostridium perfringens