Hepatitis viruses, infection and transmission (Medical Microbiology)

Multiple Choice Question of Hepatitis (A, B, and C)viruses, types, infection, and transmission

1) Which of the following organ is primarily infected by Hepatitis viruses?
a) Intestines
b) Gall bladder
c) Stomach
d) Liver

2) All of the following are the type of RNA viruses, EXCEPT?
a) Hepatitis A
b) Hepatitis B
c) Hepatitis C
d) Hepatitis D

3) Which of the following virus is NOT transmitted through the parenteral route?
a) Hepatitis A
b) Hepatitis B
c) Hepatitis C
d) Hepatitis D

4) Hepatitis A virus (HAV) belongs to which of the following family of viruses?
a) Hepadnaviridae
b) Hepeviridae
c) Picornaviridae
d) Flaviviridae

5) All of the following are the important structural characteristics of the Hepatitis B virus (HBV) EXCEPT?
a) The size of the virus is 42 nm in diameter
b) The envelope consists of surface antigen (HBsAg) and lipid
c) Consists of the single-stranded RNA genome
d) The mode of transmission is parenteral

6) All of the following statements regarding HBV infection is true, EXCEPT?
a) Acute liver infection is subclinical in about 70 percent
b) Chronic hepatitis B can lead to cirrhosis and liver cancer
c) Infants born to infected mothers can have this virus
d) Medications are not available for the treatment of the chronic hepatitis B infection

7) Which of the following is the major risk factor for the Hepatitis C virus (HCV)infection in the United States of America?
a) Sexual activity
b) Use of drugs
c) Blood transfusion
d) Tattoos

8) Hepatitis D virus is also known as the delta virus requires HBV to cause infection in people
a) TRUE
b) FALSE

9) Hepatitis E virus (HEV) infection is more commonly found in developing countries which is transmitted mostly through contaminated water, all of the following are the signs and symptoms of HEV, EXCEPT?
a) Blood in the stool
b) Nausea and vomiting
c) Yellowing of the skin
d) Low-grade fever

10) Which of the following statement is true for hepatitis causing viruses HAV, HCV, HDV, and HEV?
a) Transmitted via the fecal-oral route
b) Transmitted via the parenteral route
c) Contain a single-stranded RNA genome
d) None of the above

11) Which of the following group of people are NOT considered in the increased risk of acquiring HAV infections?
a) People traveling to developed countries to developing countries
b) Men having a sexual relationship with other men
c) People working with primates
d) Babies born to mother with HAV 

12) A 32-year-old man comes to the clinic with abdominal discomfort and vomiting, low grade, and fever, the diagnosis was done and he was found to be infected with HAV. In a blood sample, IgM antibodies detection confirms the HAV infection, how long after the initial infection these antibodies are found in the blood?
a) 24 hours
b) 3 to 4 days
c) 1 to 2 weeks
d) 12 hours

13) All of the following statements are true for the diagnosis of HBV infection, EXCEPT?
a) Tests for the detection of elevated liver enzymes should be done
b) Serological tests to detect the antigen
c) Liver function test- bilirubin
d) Glucose challenge test       

14) Which of the following statements about Hepatitis D virus is NOT correct?
a) RNA virus
b) Transmitted by parenteral route
c) Can replicate only when in a cell that is also infected by HBV
d) It primarily infects the intestinal cells

15) According to the World Health Organization's recent survey, approximately what percentage of people are living with Hepatitis infection?
a) 75 %
b) >5 %
c) 25 %
d) 50 %

16) What are the other risk factors that can cause hepatitis infection, Select all the correct answers?
a) Abuse of drugs
b) High alcohol consumption
c) Fatty liver
d) Autoimmune infection

17) Which of the following statements is NOT correct about the vaccination of HAV, HBV, and HCV?
a) Hepatitis A vaccination should be started from one year of age
b) Only newborns from infected mothers are required to get the HBV vaccine
c) There is no vaccine available for HCV
d) All of the above

18) HEV can cause epidemics of jaundice, more commonly seen in developing countries. All of the following are the most common sources of HEV, EXCEPT?
a) Contaminated water
b) Raw or undercooked pork
c) Contaminated blood products
d) A sexual relationship with an infected individual

19) All of the following statements about the HEV are true, EXCEPT?
a) Transmitted by the fecal-oral route
b) It is a non-enveloped virus
c) It is the major cause of hepatitis liver cancer
d) Found in rodents and pigs

20) Hepatitis C infection in the USA is increasing among young adults in the USA, there is more than 100 % increase since 2005 particularly seen among young adults. Which of the following is the most common cause of this infection?
a) Use of illegal intravenous drugs
b) Unsafe sex
c) Baby born to an infectious mother
d) Person who is infected with HIV

21) Recently the Nobel prize for physiology or medicine was awarded to the three scientists for the discovery of which hepatitis virus?
a) HBV
b) HCV
c) HAV
d) HEV

22) Which of the following virus may spread due to lack of good hygienic practice and through contaminated water?
a) Hepatitis B and D
b) Human papillomavirus
c) Hepatitis A and E
d) Zika virus

23) The symptoms from hepatitis A infection may persist for weeks to a month, the most common types of symptoms are fever, diarrhea, abdominal pain, and jaundice. Jaundice is the condition of yellowing of the skin due to................?
a) Low levels of bilirubin in a body
b) Low levels of hyaluronic acid in a body
c) Accumulation of hyaluronic acid in a body
d) Accumulation of bilirubin in a body
 
24) All of the following statements are correct about autoimmune hepatitis infection, Except?
a) Treatment is not available for the infection
b) Women are more affected than men
c) Chronic and persistent hepatitis may occur 
d) People with celiac disease, rheumatoid arthritis are at higher risk

25) Babies born to affected mothers with Hep B virus should be vaccinated, according to the WHO (world health organization) when is the first dose of Hep B vaccine recommended?
a) Within a week after the birth
b) 15 days after the birth
c) 72 hours of birth
d) Within 24 hours of  birth 




Answers:
1) d) Liver
2) b) Hepatitis B
3) a) Hepatitis A
4) c) Picornaviridae
5) c) Consists of the single-stranded RNA genome
6) d) Medications are not available for the treatment of the chronic hepatitis B infection
7) c) Blood transfusion
8) a) TRUE
9) a) Blood in the stool
10) c) Contain a single-stranded RNA genome
11) d) Babies born to infected mother with HAV
12) c)1 to 2 weeks
13) d) Glucose challenge test           
14) d) 
15) b) >5 %
16) All options above
17) b) Newborns from infected mothers are only required to get the HBV vaccine
18) d) A sexual relationship with the infected individual
19) c) The major cause of hepatitis liver cancer
20) a) Injecting drug use
21) b) HCV
22) c) Hep A and E
23) d)
24) a)
25) d)

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