MCQ on Yersinia Pestis & Pasteurella sps (Medical Microbiology)

Multiple Choice Question on Yersinia sps and Pasteurella sps (Gram negative bacteria)

1) All of the following bacterial pathogens given below are the example of major zoonotic diseases, EXCEPT
a) Bacillus anthracis
b) Borrelia burgdorferi
c) Yersinia pestis
d) Leishmania tropica

2) Which of the following is the most common form of plague which causes swelling of the lymph nodes?
a) Septicemic plague
b) Bubonic plague
c) Pneumonic plague
d) All of the above

3) Which of the following statements is NOT correct about the cultural characteristics of Yersinia pestis?
a) The bacteria can cause pneumonia in humans through airborne droplets 
b) The suitable bacterial growth temperature is room temperature using MacConkey agar
c) The bacteria is lactose positive
d) The common source of transmission to humans is through rats 

4) Select all the correct answers, the commonly used preventive measures to control the plague are.........
a) Patients diagnosed with the infection should be isolated and quarantined
b) The laboratory specimens should be handled in the biological safety cabinet
c) The control of rodents should be done by finding its habitat and destructing it
d) Protective wear, gloves and insect repellent cream should be used in the endemic areas

5) All of the statements given below about the Yersinia enterocolitica is correct, EXCEPT
a) The bacteria is gram negative, non-motile 
b) Consist of bipolar staining property
c) The most common serotypes causing human gastroenteritis is O:1
d) Most commonly transmitted to humans through infected food, water and animals 

6) What is the recommended drug regimen for Yersinia enterocolitica infections?
a) Penicillin
b) Ampicillin with cefalotin
c) Doxycycline with aminoglycoside
d) Penicillin G

7) Which of the following is the selective media used for the isolation of the pathogen Yersinia enterolitica from a stool specimen?
a) Regan lowe medium
b) Celfsulodin-irgasan-novobiocin agar
c) MacConkey agar
d) Lowenstein-Jensen media

8) Which of the following pathogen can be transferred to human and cause infections from the bite of dogs and cats?
a) Yersinia pseudotuberculosis
b) Pasteurella multocida
c) Yersinia enterolitica
d) Pasteurella pneumotropica

9) Which of the following is the drug of choice for infections caused by Pasteurella multocida?
a) Ampicillin
b) Tetracyclines
c) Penicillin G
d) Doxycycline

10) Which of the following is NOT the possible pathogen isolated from infections of the human genital tract and may transmit from mother to the newborns?
a) Treponema pallidum
b) Toxoplasma gondii
c) Pasteurella bettyae
d) Campylobacter jejuni

11) The asymptomatic individuals in exposure to untreated people with pneumonic plague and laboratory personnel working with handling the specimens should be given the antibiotic prophylaxis for a given period of time, what is the drug usually used for the prophylaxis?
a) Rifampin
b) Penicillin
c) Erythromycin
d) Doxycycline

12) All of the following are the possible laboratory methods used for the diagnosis of Bubonic plague, EXCEPT
a) Blood culture on MacConkey agar
b) Stool culture on Chocolate agar
c) Aspirates culture in brain heart infusion broth taken from swollen lymph nodes
d) Wayson stain method for the identification of the suspected bacteria

13) All of the statements given below are correct about the diagnosis of Yersinia pseudotuberculosis related infection in humans, EXCEPT
a) Appendicitis-like symptoms may be observed
b) Presented as mesenteric lymphadenitis
c) Tuberculosis like symptoms may be seen in laboratory animals after bacterial inoculation
d) Genetic features are similar to Yersinia enterolitica

14) Pasteurella multocida have been found as a normal flora in the respiratory tract of which of the following animals?
a) Cats
b) Deer
c) Pigeons
d) Bats

15) In addition to membrane lipopolysaccharide endotoxins, Yersinia pestis possesses other virulent plasmids. They include
a) pPCP1 that encodes for a plasminogen-activating protease
b) pFra/pMT that encodes for a capsular protein that has antiphagocytic activity
c) pFra/pMT that encodes for phospholipase D crucial for survival in flea gut
d) All of the above

16) All of the following are primary pathogens found in rodents are the gram negative, short bacilli, Except?
a) Campylobacter jejuni
b) Pasteurella multocida 
c) Francisella tularensis
d) Yersinia pseudotuberculosis
e) Leishmania tropica
f)  Yersinia pestis

17) Which of the following statements is Not correct about the disease Tularemia?
a) Most commonly transmitted through the poultry to humans
b)The skin, respiratory tract are the primary sites of infection
c) Prevalent in different states of the USA
d) It is caused by a gram negative small bacilli 

18) The outbreak of black death, a pandemic during the 1300s killed millions of people in Europe and Asia. Name the possible pathogen found to be responsible for the outbreak?
a) Francisella tularensis
b) Yersinia pestis
c) Yersinia pseudotuberculosis
d) Pasteurella haemolytica







Multiple Choice Answers
1-d) Leishmania tropica
2-b) Bubonic plague
3-c) The bacteria is lactose positive
4- a) b) c) and d 
5-c) The most common serotypes causing human gastroenteritis is O:1
6-c) Doxycycline with aminoglycoside
7-b) Celfsulodin-irgasan-novobiocin agar
8-b) Pasteurella multocida
9-d) Doxycycline
10-d) Campylobacter jejuni
11-d) Doxycycline
12-b) Stool culture on Chocolate agar
13-d) Genetic features are similar to Yersinia enterolitica
14-a) Cats
15-d) All of the above
16- a) and e)
17- a) Most commonly transmitted through the poultry to humans
18- b) Yersinia pestis
19- 
20- 



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