MCQ on Yersinia Pestis & Pasteurella sps (Medical Microbiology)

Multiple Choice Question on Yersinia sps and Pasteurella sps

1) All of the following bacterial pathogens given below are the example of major zoonotic diseases, EXCEPT
a) Bacillus anthracis
b) Borrelia burgdorferi
c) Yersinia pestis
d) Leishmania tropica

2) Which of the following is the most common form of plague which causes swelling of the lymph nodes?
a) Septicemic plague
b) Bubonic plague
c) Pneumonic plague
d) All of the above

3) Which of the following statements is NOT correct about the cultural characteristics of Yersinia pestis?
a) It grows rapidly on blood culture compared to other culture media
b) The suitable growth temperature for the pathogen is the room temperature when grown on MacConkey agar
c) The colonies appear as lactose positive on MacConkey agar
d) These bacteria are nonmotile

4) Select from all the options below that are commonly used as preventive measures to control the plague.
a) Patients diagnosed should be isolated
b) The specimens should be handled in the biological safety cabinet
c) The control of rodents should be done by finding its habitat and destructing it
d) Prophylactic antibiotic therapy should be given to individuals who have been exposed to the person who is diagnosed with plague

5) All of the statements given below about the Yersinia enterocolitica is correct, EXCEPT
a) The pathogens do not possess motility
b) Consist of bipolar staining property
c) The most common serotypes causing human gastroenteritis is O:1
d) Transmitted to humans through contaminated food and contact with infected animals

6) What is the recommended drug regimen for Yersinia enterocolitica infections?
a) Penicillin
b) Ampicillin with cefalotin
c) Doxycycline with aminoglycoside
d) Penicillin G

7) Which of the following is the selective media used for the isolation of the pathogen Yersinia enterolitica from a stool specimen?
a) Regan lowe medium
b) Celfsulodin-irgasan-novobiocin agar
c) MacConkey agar
d) Lowenstein-Jensen media

8) Which of the following pathogen can be transferred to human and cause infections from the bite of dogs and cats?
a) Yersinia pseudotuberculosis
b) Pasteurella multocida
c) Yersinia enterolitica
d) Pasteurella pneumotropica

9) Which of the following is the drug of choice for infections caused by Pasteurella multocida?
a) Ampicillin
b) Tetracyclines
c) Penicillin G
d) Doxycycline

10) Which of the following is NOT the possible pathogen isolated from infections of the human genital tract and of newborns?
a) Treponema pallidum
b) Toxoplasma gondii
c) Pasteurella bettyae
d) Campylobacter jejuni

11) The asymptomatic individuals in exposure to untreated people with pneumonic plague and laboratory personnel working with handling the specimens should be given the antibiotic prophylaxis for a given period of time, what is the drug usually used for the prophylaxis?
a) Rifampin
b) Penicillin
c) Erythromycin
d) Doxycycline

12) All of the following are the possible laboratory methods used for the diagnosis of Bubonic plague, EXCEPT
a) Blood culture on MacConkey agar
b) Stool culture on Chocolate agar
c) Aspirates culture in brain heart infusion broth taken from swollen lymph nodes
d) Wayson stain method for the identification of the suspected bacteria

13) All of the statements given below are correct about the diagnosis of Yersinia pseudotuberculosis related infection in humans, EXCEPT
a) Appendicitis-like symptoms may be observed
b) Presented as mesenteric lymphadenitis
c) Tuberculosis like symptoms may be seen in laboratory animals after bacterial inoculation
d) Genetic features are similar to Yersinia enterolitica

14) Which of the following species of Pasteurella is present as normal flora of respiratory tract and guts of mice and rats?
a) Pasteurella pneumotropica
b) Pasteurella bettyae
c) Pasteurella multocida
d) Pasteurella anatis

15) In addition to membrane lipopolysaccharide endotoxins, Yersinia pestis possesses other virulent plasmids. They include
a) pPCP1 that encodes for a plasminogen-activating protease
b) pFra/pMT that encodes for a capsular protein that has antiphagocytic activity
c) pFra/pMT that encodes for phospholipase D crucial for survival in flea gut
d) All of the above
Multiple Choice Answers
1-d) Leishmania tropica
2-b) Bubonic plague
3-c) The colonies appear as lactose positive on MacConkey agar
4-All of the above a, b,c, d
5-c) The most common serotypes causing human gastroenteritis is O:1
6-c) Doxycycline with aminoglycoside
7-b) Celfsulodin-irgasan-novobiocin agar
8-b) Pasteurella multocida
9-d) Doxycycline
10-d) Campylobacter jejuni
11-d) Doxycycline
12-b) Stool culture on Chocolate agar
13-d) Genetic features are similar to Yersinia enterolitica
14-a) Pasteurella pneumotropica
15-d) All of the above

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