MCQ on Influenza Virus & Influenza Subtypes (Type A, B & C) (Medical Microbiology)

Influenza Virus & Subtypes (Flu virus) Type A, B, & C
Multiple Choice Questions

1) Identify the False statement about the influenza viruses subtypes A, B, and C: 
a) Influenza type A may be found in chickens, pigs, and horses
b) Antigenic shifts or viral genome reassortment occurs in Influenza A virus
c) All three types of viruses are found in humans and other animals
d) Influenza virus infects mainly the upper respiratory tract

2)The properties of Orthomyxoviridae include all of the following statements, EXCEPT:
a) The virus consists of single-stranded RNA
b) The outer envelope of the virus is made up of lipid bilayer
c) The size of the virus (150nm) is larger than the Paramyxoviruses  
d) The hemagglutinin and neuraminidase of the influenza virus helps it to attach to the host cells

3) Which of the following are NOT the common symptoms of flu caused by the influenza virus in adults?
a) Fever
b) Cough
c) Rashes
d) Headache

4) Which of the following virus can give lifelong immunity to the disease after prior infection or immunization?
a) Rhinovirus
b) Influenza A virus
c) Influenza C virus
d) Measles virus

5) Identify the influenza virus serotype that causes most of the epidemics:
a) Type A
b) Type B
c) Type C
d) None of the above

6) Which of the following person can be at risk of contracting the flu? 
Choose the correct answer:
a) A 70-year-old woman
b) A  healthy 4-year-old boy
c) A 35-year-old man with diabetes
d) All of the above

7) The most common route of the transmission of the influenza virus is airborne droplets. 
Which of the following type of the virus is considered highly contagious and is known to spread rapidly from person to person?
a) Influenza A
b) Rhinovirus
c) Influenza B
d) All of the above

8) Which of the following microorganism is the common cause of secondary infection that can be seen with influenza virus infection?
a) Rhinovirus
b) Staphylococcus aureus
c) Rubella virus
d) Chlamydia pneumoniae

9) All of the following statements are correct about the Neuraminidase (NA) and Hemagglutinin (HA) of influenza virus, EXCEPT?
a) Helps the virus to bind to host cell surface
b) Both of the antigens are embedded in the outer surface of the viral envelope
c) Neuraminidase is present as a spike and is composed of dimers
d) Frequent antigenic changes occur in NA and HA

10) A 16-year-old girl came to the clinic with a sore throat, fever, and headache, the symptoms resembled seasonal influenza flu. 
Which of the following primary samples/specimen is collected for the laboratory diagnosis of the influenza virus?
a) Blood
b) Sputum
c) Urine
d) Nasopharyngeal washing

11) Which of the following statements about isolation and identification of influenza is NOT correct?
a) The specimen should be kept at 4 degree Celsius
b) Culture of the virus is usually done by using embryonated eggs
c) The specimens should be taken within 1 to 3 days after the onset of symptoms
d) Rapid antigen detection tests cannot be done

12) Major antigenic changes in HA or NA are known as an antigenic shift which results in a new influenza virus subtype, True or False?
a) True
b) False

13)Which of the following is a reservoir for the antigenic shift variants of the influenza virus?
a) Pigs and horses
b) Rodents
c) Mosquitoes
d) Human

14) Which of the following statement is NOT correct about the preventive measures of the influenza virus?
a) Washing hands more often helps
b) A sick person with flu should stay isolated at least for 24 hours
c) Over the counter (OTC) antiviral drugs are available for the influenza virus
d) Live attenuated and inactivated viruses both are used for vaccination

15) Identify the source of H5N1 infection in humans?
a) Birds
b) Pigs
c) Ferrets
d) None of the above

16) In what year did the influenza pandemic kill millions of people?
a) 1945
b) 1900
c) 1928
d) 1918

17) Influenza virus can be easily killed by using all of the following agents. 
Select all the correct answers
a) High heat
b) Water
c) Ethanol
d) Detergents

18) Since the symptoms caused by the influenza virus and COVID-19 are similar, the flu vaccine can prevent COVID-19 infections
a) TRUE
b) FALSE

Answers:
1-c) All three types of viruses are found in humans as well as animals
2-c) The size of the virus (150nm) is larger than the Paramyxoviruses
3-c) Rashes
4-d) Measles virus
5-a) Type A
6-d) All of the above
7-a) Influenza A
8-b) Staphylococcus aureus
9-c) Neuraminidase is present as a spike and is composed of dimers
10-d) Nasopharyngeal washing
11-d) Rapid antigen detection tests cannot be done
12-a) True
13-a) Pigs and horses
14-c) Over the counter antiviral drugs are available for the influenza virus
15-a) Birds
16-d) 1918
17-a), c) and d)
18-b) FALSE

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