Medical Microbiology: Influenza Virus Type A, B & C

Influenza Virus Type A, B, & C
Multiple Choice Questions

1) Identify the False statement about influenza viruses A, B, and C: 
a) Influenza type A may be found in chickens, pigs, and horses
b) Antigenic shifts or viral genome reassortment occurs in Influenza A virus
c) All three types of viruses are found in humans and other animals
d) Influenza virus infects mainly the upper respiratory tract

2)The properties of Orthomyxoviruses include all of the following statements, EXCEPT:
a) The virus consists of single-stranded RNA
b) The outer envelope of the virus is made up of lipid bilayer
c) The size of the virus (150nm) is larger than the Paramyxoviruses  
d) The hemagglutinin and neuraminidase of the influenza virus helps it to attach to the host cells

3) Which of the following is NOT the common symptoms of flu caused by the influenza virus in adults?
a) Fever
b) Cough
c) Rashes
d) Headache

4) Which of the following viruses gives lifelong immunity to disease after prior infection or immunization?
a) Rhinovirus
b) Influenza A virus
c) Influenza C virus
d) Measles virus

5) Identify the influenza virus serotype that causes most of the epidemics:
a) Type A
b) Type B
c) Type C
d) None of the above

6) Which of the following subjects are at risk of getting influenza flu? Choose the correct answer
a) A 70-year-old woman
b) A  healthy 4-year-old boy
c) A 35-year-old man with diabetes
d) All of the above

7) The most common route of the pathogenesis of influenza virus is airborne droplets, which of the following virus is most likely to cause a pandemic?
a) Influenza A
b) Rhinovirus
c) Influenza B
d) All of the above

8) Which of the following microorganism is a co/secondary cause of pneumonia caused by the influenza virus?
a) Rhinovirus
b) Staphylococcus aureus
c) Rubella virus
d) Chlamydia pneumoniae

9) All of the following statements are correct about the Neuraminidase (NA) and Hemagglutinin (HA) of influenza virus, EXCEPT?
a) Helps the virus to bind to host cell surface
b) Both of the antigens are embedded in the outer surface of the viral envelope
c) Neuraminidase is present as a spike and is composed of dimers
d) Frequent antigenic changes occur in NA and HA

10) A 16-year-old girl comes to the clinic with a sore throat, fever, and headache, the symptoms resembled the flu-like syndrome. Which of the following the primary sample/specimen is collected for the laboratory diagnosis of influenza virus?
a) Blood
b) Sputum
c) Urine
d) Nasopharyngeal washing

11) Which of the following statements about isolation and identification of influenza is NOT correct?
a) The specimen should be kept at 4 degree Celsius
b) Culture of the virus is usually done by using embryonated eggs
c) The specimens should be taken within 1 to 3 days after the onset of symptoms
d) Rapid antigen detection tests cannot be done

12) Major antigenic changes in HA or NA is known as an antigenic shift which results in a new influenza virus subtype, True or False?
a) True
b) False

13)Which of the following is a reservoir for the antigenic shift variants of influenza virus?
a) Pigs and horses
b) Rodents
c) Mosquitoes
d) Human

14) Which of the following statement is NOT correct about the preventive measures of influenza virus?
a) Washing hands more often helps
b) A sick person with flu should stay isolated at least for 24 hours
c) Over the counter (OTC) antiviral drugs are available for influenza virus
d) Live attenuated and inactivated virus both are used for vaccination

15) Identify the source of H5N1 infection in humans?
a) Birds
b) Pigs
c) Ferrets
d) None of the above


1-c) All three types of viruses are found in humans as well as animals
2-c) The size of the virus (150nm) is larger than the Paramyxoviruses
3-c) Rashes
4-d) Measles virus
5-a) Type A
6-d) All of the above
7-a) Influenza A
8-b) Staphylococcus aureus
9-c) Neuraminidase is present as a spike and is composed of dimers
10-d) Nasopharyngeal washing
11-d) Rapid antigen detection tests cannot be done
12-a) True
13-a) Pigs and horses
14-c) Over the counter antiviral drugs are available for influenza virus
15-a) Birds