MCQ on Subcutaneous Mycoses (Medical Mycology)

Multiple Choice Question on
MCQ on Subcutaneous Mycoses

1) A 35-year-old man residing in Mexico comes to the hospital with an ulcerative lesion in his left thumb and have been suffering for 10 days. He got a cut while taking care of the plants in his garden and the lesion in thumb started to spread to the forearm with abscesses. The sample from the infected site was cultured for fungal examination, cream-colored colony appeared within 3 days. The colony growth appeared brown after few days and it changed to black  and fuzzy in appearance after a week of incubation, which of the following is the likely pathogen?
a) Epidermophyton flocussum
b) Tinea versicolor
c) Sporothrix schenckii 
d) Basidiobolus ranarum

2) Which of the following is NOT the cultural characteristics of fungus causing subcutaneous mycoses?
a) Classification Includes dimorphic fungi
b) The infections are caused by saprophytic fungi
c) It usually occurs in tropical regions
d) Majority of fungi causes superficial skin infections 

3) Which is the other likely pathogen that mimics the skin lesions same as of Sporothrix schenckii when observed under the microscope?
a) Rickettsia spp
b) Nocardia spp 
c) Aspergillus
d) None of the above

4) All of the following statements are true about dematiaceous fungi, EXCEPT?
a) They have dark pigments in their cell wall
b) Induce a granulomatous reaction
c) Formation of conidia in cultures
d) Reproduces by sexual process 

5) All of the following organism cause Chromoblastomycosis, EXCEPT?
a) Phialophora verrucosa
b) Fonsecaea compacta
c) Fonsecaea pedrosoi
d) Exophilia dermatidis 

6) Which of the following is the most correct statement about eumycotic mycetoma?
a) It is characterized by infectious granulomas and abscesses 
b) The disease is more frequent in colder regions
c) It spreads from one person to another very easily
d) The mycoses are usually superficial

7) What are the primary sites of invasion in eumycotic mycetoma?
a) Neck and face
b) Hair shafts
c) Legs and hands 
d) Chest and back

8) Which of the following is the main etiological agent for mycoses of foot mostly occurring in the Indian subcontinent and the middle east?
a) Sporothrix schenckii
b) Phialophora verrucosa
c) Conidiobolus coronatus
d) Madurella mycetomatis 

9) Which of the following is the most common likely pathogen that causes actinomycotic mycetoma?
a) Madurella spp
b) Nocardia spp 
c) Exophiala spp
d) Fusarium spp

10) Which of the following is the commonly used laboratory diagnosis method of eumycotic mycetoma?
a) Demonstration of granules from abscesses by microscopy 
b) Histopathologic examination of an inflammatory cyst
c) Microscopic identification of fungi in skin scrapings from warty lesions
d) The culture isolation of the fungi from infected pus

11) Which of the following statement is true about the treatment of eumycotic mycetoma?
a) Administration of itraconazole and potassium iodide solution is effective
b) Surgery or amputation is the choice of treatment in most cases 
c) Amphotericin B and Ketoconazole are the drugs of choice
d) None of the above

12) Which of the following is the etiological agent of subcutaneous mucor mycosis?
a) Madurella mycetomatis
b) Conidiobolus coronatus 
c) Exophilia jeanselmei
d) Fonsecaea compacta

13) Which fungi are responsible for the subcutaneous mycoses most primarily affecting the nasal cavity and face?
a) Histoplasma capsulatum
b) Basidiobolus ranarum
c) Blastomyces dermatitidis
d) Conidiobolus corronatus 

14) Which of the following is the drug of choice for sporotrichosis?
a) Itraconazole 
b) Amphotericin B
c) Ketoconazole
d) Posaconazole

15) What is the type of lesions mostly seen in chromoblastomycosis?
a) Abscesses with granulomas
b) Painless lesions having a cyst
c) Dark pigmented wart like skin lesions
d) All of the above

16) "Madura foot" was first diagnosed in India in during 1800s
a) True
b) False

17) A 14 year old boy is presented to the hospital with swollen upper part of the left thigh since 6 months, the boy did not had any particular symptoms like fever and did not feel pain in the swollen area in the past or during the physical examination . The tissue sample was taken for the laboratory examination, wide aseptate hyphae were observed under the microscope. Fungal culture method was performed, waxy, yellow and round colonies appeared after few days of incubation. Which of the following could be the possible fungi?
a) Rhinosporidium spp 
b) Basidiobolus spp
c) Aspergillus spp
d) Rhizopus spp

18) From the above question, the fungi responsible for the infection is also called the following type of mycosis 
a) Phaeohyphomycosis
b) Aspergillosis
c) Hyalohyphomycosis
d) Subcutaneous phycomycosis

19) Which of the following statements is Not correct regarding chromoblastomycosis?
a) It is the disease condition caused by dematiaceous fungi
b) People working with soil, usually in rural areas can develop the disease
c) It is mostly seen as a opportunistic infection in immunocompromised patients
d)Examination of the tissues show the "sclerotic bodies" in chromoblastomycosis
e)Examination of the tissues show the "asteroid bodies" in chromoblastomycosis
f) It is presented usually with a painless swollen pigmented lesions

20) All of the following are the fungi causing mycotic mycetoma, Except?
a) Nocardia brasiliensis
b) Fusarium solani
c) Actinomadura madurae
d) Aspergillus niger
e) Nocardia asteroides
f) Madurella mycetomatis

1-c) Sporothrix schenckii 
2-d) Majority of fungi causes superficial skin infections 
3-b) Nocardia spp 
4-d) Reproduces by sexual process 
5-d) Exophilia dermatidis 
6-a) It is characterized by infectious granulomas and abscesses 
7-c) Legs and hands 
8-d) Madurella mycetomatis 
9-b) Nocardia spp 
10-a) Demonstration of granules from abscesses by microscopy 
11-b) Amputation is the choice of treatment in most cases 
12-b) Conidiobolus coronatus 
13-d) Conidiobolus corronatus 
14-a) Itraconazole 
15-c) Dark pigmented wart like skin lesions 
16-a) True
17-b) Basidiobolus spp
18)-d) Subcutaneous phycomycosis
19- e) 
20- d) Aspergillus niger

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