MCQ on Opportunistic Mycoses (Candida albicans, Aspergillus flavus, Cryptococcus neoformans)

Opportunistic Mycoses, Aspergillus flavus and other fungi
Multiple Choice Questions

1) Which of the following disease is the example of opportunistic mycoses?
a) Aspergillosis
b) Salmonellosis
c) Listeriosis
d) Sporotrichosis

2) Which of the following statement is NOT the general characteristics of Candida albicans?
a) It is found as a yeast or hyphae form 
b) Part of the normal human flora
c) The primary cause of yeast infections in human  
d) All of the above

3) Which of the following pathogenic fungi is the member of human microbiota?
a) Aspergillus niger
b) Cryptococcus neoformans
c) Candida albicans 
d) Rhizopus oryzae

4) Zygomycosis is caused by:
a) Cryptococcus neoformans
b) Rhizopus oryzae 
c) Aspergillus fumigatus
d) Penicillium marneffei

5) A 11 years old girl comes to a clinic with white lesions around the mouth and tongue, the girl has developed fever, swelling, and pain around the infected area. Swab specimen is taken and microscopic examination showed budding spherical cells with hyphae. After 24 hours of culture of the specimen, smooth cream-colored colonies are observed. Name the most possible pathogen responsible for the infection?
a) Rhizopus oryzae
b) Aspergillus fumigatus
c) Pneumocystis jiroveci
d) Candida albicans 

6) All of the following are the morphological characteristics of Cryptococcus neoformans, EXCEPT?
a) It is a capsulated yeast
b) Produces urease
c) Cannot be isolated in a laboratory
d) None of the above

7) Pulmonary Aspergilloma is usually common in patients infected who have …............?
a) Peptic ulcer
b) Cystic fibrosis
c) Multiple sclerosis
d) Cirrhosis

8) Which of the following fungal pathogen grows in pigeon droppings (excreta)?
a) Cryptococcus neoformans
b) Coccidioides immitis
c) Penicillium marneffei
d) Pneumocystis jiroveci

9) Which of the following fungi produces carcinogenic toxic metabolites?
a) Aspergillus fumigatus
b) Cryptococcus neoformans
c) Coccidioides immitis
d) Aspergillus flavus 

10) Which of the following product is most commonly infected by Aspergillus flavus?
a) Nuts  
b) Bread
c) Honey
d) Grapes

11) A 50 years old man suffered a burn injury in the right arm, after a few days he developed blisters and ulcers around the burnt area. When examined redness and swelling around the infected area is observed. Fungal infection was suspected and biopsy was done, direct microscopic examination showed thick, branched septate hyphae with a black round tip. In culture, cottony colonies can be observed after a few hours of incubation. Name the possible pathogen responsible for the infection?
a) Pneumocystis jeroveci
b) Rhizopus oryzae 
c) Coccidioides immitis
d) Aspergillus flavus

12) Which of the following antibiotics is most effective for the treatment for pulmonary aspergilloma?
a) Penicillin G
b) Fluconazole
c) Ketoconazole
d) Amphotericin B

13) Name the fungal infection which is most commonly seen in patients with advanced HIV/AIDS with the wart-like skin lesions which often appear on the face?
a) Mucormycosis
b) Histoplasmosis
c) Penicillosis
d) Blastomycosis

14) Which of the following human fungal species also present in the lungs of animals, causes pneumonia in immunocompromised patients?
a) Aspergillus niger
b) Pneumocystis jiroveci 
c) Penicillium marneffei
d) All of the above

15) Which of the following fungi causes vaginal thrush?
a) Candida albicans 
b) Rhizopus oryzae
c) Candida tropicalis
d) Aspergillus fumigatus

16) Which of the following fungus is not the type of fungi associated with emerging opportunistic fungal infections in AIDS patients?
a. Fusarium chlamydosporum
b. Penicillium marneffei
c. Trichosporon beigelii
d. Rhizopus stolonifer     

17) In recent years, opportunistic mycoses in immunocompromised individuals is caused by various types fungi including molds, all of the following are the examples of yeasts and molds, EXCEPT?
a. Aspergillus niger
b. Histoplasma capsulatum    
c. Acremonium spp
d. Fusarium spp
e. Trichosporon beigelii
f. Candida krusei

18) All of the following are the common sites of infections caused by C. albicans, Except?
a. Mouth
b. Throat     
c. Groin of infants
d. Vaginal area

19) Which of the following is Not the common characteristics of  A. fumigatus and A. flavus?
a. Both of the organisms secrete aflatoxins    
b. Present in the environment
c.  A. flavus is also a common plant pathogen
d. Both fungi are types of molds

20) Fusarium spp is one of the most common fungal pathogen which causes infections in immunocompromised patients, which of the following statement is Not true for the pathogen?
a. Found in soils
b. Skin infections in human
c. Commensal of respiratory tract
d. A common plant pathogen

1- a) Aspergillosis 
2- d) All of the above 
3- c) Candida albicans 
4- b) Rhizopus oryzae 
5- d) Candida albicans 
6- c) Cannot be isolated in laboratory 
7- b) Cystic fibrosis 
8- a) Cryptococcus neoformans 
9- d) Aspergillus flavus 
10-a) Nuts 
11-b) Rhizopus oryzae 
12-d) Amphotericin B 
13- c) Penicillosis 
14- b) Pneumocystis jiroveci 
15-a) Candida albicans 
16-d) Rhizopus stolonifer
17-b) Histoplasma capsulatum
18-b) Throat
19)-a) Both of the organisms secrete aflatoxins
20)-c) Commensal of respiratory pathogen