MCQ on Mycoplasma sps (Medical Microbiology)

Multiple Choice of Question on Mycoplasma species
1) Which of the following are the common human infections caused by Mycoplasma spp
Select the correct answers from the options given below
a) Pneumonia
b) Food poisoning
c) Urethritis
d) Skin infections

2) All of the following are the general characteristics of Mycoplasma spp, EXCEPT?
a) It can grow on cell-free media containing lipoprotein and sterol
b) They are pleomorphic and very small in size
c) They are best identified using a gram staining technique
d) Colonies appear as a fried egg in shape in the media 
e) The bacteria are aerobic/facultative anaerobic
f) Do not consist of flagella or spores

3) A 14-year-old boy contracts cough and fever at school where one of his friends from the class had the same symptom for a few days. At the hospital, laboratory sputum culture and gram staining method showed negative results and chest radiography results also did not demonstrate the infection area properly. 
Which is the likely pathogen?
a) Mycoplasma hominis
b) Mycoplasma pneumoniae
c) Mycobacterium leprae
d) Ureaplasma urealyticum

4) Which of the following statements is true about Ureaplasma urealyticum?
a) It can be cultivated in routine culture medium
b) The transmission of the bacteria is through the respiratory passage
c) The bacteria can grow easily in media containing urea 
d) It is susceptible to penicillin and amoxicillin

5) Mycoplasma spp are resistant to the drug Penicillin
a) True
b) False

6) A blood sample from a 19-year-old sexually active woman with genital infections was taken and cultured for the isolation of the responsible pathogen. 
Name the least likely pathogen that can be responsible for the infection?
a)Chlamydia trachomatis
b)Mycoplasma hominis
c)Mycoplasma pneumoniae
d)Mycoplasma genitalium

7) Select the primary pathogens of genital infections 
a) Mycoplasma pneumoniae
b) Mycoplasma hominis
c) Ureaplasma urealyticum
d) All of the above

8) The routine laboratory diagnostics method is usually not helpful for the isolation and identification of Mycoplasma pneumoniae
All of the following are the important clinical tests for the diagnosis of the infection in humans caused by M.pneumoniae, EXCEPT?
b) Complement fixation
c) Cold hemagglutinins
d) Electron microscopy

9) Which of the following pathogens commonly cause 'community-acquired pneumonia'? 
Select from all the options given below
a)Streptococcus pneumoniae
b)Chlamydia trachomatis
c) Mycoplasma pneumoniae
d) Haemophilus influenzae

10) Which of the following Mollicutes is associated with the infection “salpingitis” and “postpartum fever”?
a) Mycoplasma genitalium
b) Ureaplasma urealyticum
c) Mycoplasma hominis
d) Mycoplasma pneumoniae

11) Which of the following Mycoplasma spp grow rapidly in both broth and agar medium?
a) Ureaplasma urealyticum
b) Mycoplasma genitalium
c) Mycoplasma pneumoniae
d) None of the above

12) Ureaplasma urealyticum is found as normal flora of the urinary tract in sexually active men and women, about what percentage of women have it?
a) 20 to 40%
b) 40 to 80 % 
c) 5 to 20 %
d) 25 to 45%

13) Mycoplasma pneumoniae infections are most prevalent in what age group of people?
a) 15 to 60
b) 5 to 45
c) 5 to 20
d) 10 to 50

14) Which of the following statements is true regarding the pathogenesis of Mycoplasma infections?
a) Adherence to the host cells is mediated by the bacterial proteins
b) The bacteria enter the host cell by releasing exotoxin
c) Inhibited by beta-lactam antibiotics
d) All of the above

15) Which of the following is the drug of choice for Ureaplasma urealyticum infections?
a) Penicillin
b) Tetracyclines
c) Cephalosporins
d) Imipenem

16) Which of the following virulence factor is present in Mycoplasma pneumoniae, also known as Community-acquired distress syndrome toxin?
a) Endotoxin
b) Capsule
c) Lipid
d) Exotoxin

17) Mycoplasma pneumoniae can cause extrapulmonary infections and can infect mucous membranes and cutaneous membranes. Symptoms usually include rashes, soreness, and inflammation of these membranes.
Name the commonly used term for this type of infection?
a) Sporotrichosis
b) Epiglottitis
c) Mucositis
d) Cellulitis

18)What are the different types of infections commonly associated with M. genitalium?
Select all the correct answers:
a) Nongonococcal urethritis in men and women 
b) Pelvic inflammatory disease in women
c) Trachoma
d) Gonorrhoea
e) Infertility in women

19) Due to the lack of cell wall, the drug penicillin is not effective against M. genitalium, and the bacteria have shown high resistance to azithromycin and other macrolides. 
Name the drug used for the treatment of infections associated with M.genitalium
a) Moxifloxacin
b) Ceftriaxone
c) Acyclovir
d) Retrovir


Multiple Choice Answers Review:
1)- a) Pneumonia, c) Urethritis
2)- c) Can be identified using the gram staining technique
3)- b) Mycoplasma pneumoniae
4)- c) It requires urea for its growth
5)- a) True
6)- c) Mycoplasma pneumoniae
7)- b) Mycoplasma hominis and c)Ureaplasma urealyticum
8)- d) Electron microscopy
9)- a) Streptococcus pneumoniae, c) Mycoplasma pneumoniae, d) Haemophilus influenzae
10)- c) Mycoplasma hominis
11)- a) Ureaplasma urealyticum
12)- b) 40 to 80 %
13)- c) 5 to 20
14)- a) Adherence to the host cells is mediated by the bacterial proteins
15)- b) Tetracyclines
16- d) Exotoxin
17- c) Mucositis
18- a), b) and e)
19- a)Moxifloxacin