MCQs on Mycoplasma spp: Medical Microbiology

Multiple Choice of Questions on Mycoplasma species

1) Which of the following are the common human infections caused by Mycoplasma spp
Select the correct answers from the options given below
a) Pneumonia
b) Food poisoning
c) Urethritis
d) Skin infections

2) All of the following are the cultural characteristics of Mycoplasma spp, EXCEPT?
a) They usually grow well in anaerobic or microaerophilic conditions
b) They appear as large in size in culture media
c) The cultures grow relatively slowly compared to other bacteria
d) The colonies resemble fried egg in shape in the media 

3) A 14-year-old boy develops a cough and fever after being exposed to a classmate with similar symptoms. Gram stain and culture tests confirm Mycoplasma pneumoniae. 
Which of the following is the commonly used antibiotic for the treatment of infection caused by M. pneumoniae?
a) Rifampin
b) Sulfonamides
c) Tetracyclines
d) Vancomycin

4) Which of the following statements is true about Ureaplasma urealyticum?
a) It can be cultivated in routine culture medium
b) The transmission of the bacteria is through the respiratory passage
c) The bacteria can grow easily in media containing urea 
d) It is susceptible to penicillin and amoxicillin

5) Mycoplasma spp are resistant to the drug Penicillin
a) True
b) False

6) A blood sample from a 19-year-old sexually active woman with genital infections was taken to culture and isolate the causative agent. 
Identify the pathogen that is least likely to be responsible for the infection?
a)Chlamydia trachomatis
b)Mycoplasma hominis
c)Mycoplasma pneumoniae
d)Mycoplasma genitalium

7) Select the common pathogens of genital infections 
a) Mycoplasma pneumoniae
b) Mycoplasma hominis
c) Ureaplasma urealyticum
d) All of the above

8) The routine laboratory diagnostics method is usually not helpful for the isolation and identification of Mycoplasma pneumoniae
All of the following are the important clinical tests for the diagnosis of the infection in humans caused by M.pneumoniae, EXCEPT?
b) Complement fixation
c) Cold hemagglutinins
d) Electron microscopy

9) Which of the following pathogens commonly cause 'community-acquired pneumonia'? 
Select from all the options given below
a)Streptococcus pneumoniae
b)Chlamydia trachomatis
c) Mycoplasma pneumoniae
d) Haemophilus influenzae

10) Which of the following Mollicutes is associated with the infection “salpingitis” and “postpartum fever”?
a) Mycoplasma genitalium
b) Ureaplasma urealyticum
c) Mycoplasma hominis
d) Mycoplasma pneumoniae

11) Which of the following Mycoplasma spp grow rapidly in both broth and agar medium?
a) Ureaplasma urealyticum
b) Mycoplasma genitalium
c) Mycoplasma pneumoniae
d) None of the above

12) Ureaplasma urealyticum is found as normal flora of the urinary tract in sexually active men and women, approximately what percentage of women have the bacteria as a normal flora?
a) 20 to 40%
b) 40 to 80 % 
c) 5 to 20 %
d) 25 to 45%

13) Mycoplasma pneumoniae infections are most prevalent in what age group of people?
a) 15 to 60
b) 5 to 45
c) 5 to 20
d) 10 to 50

14) Which of the following statements is true regarding the pathogenesis of Mycoplasma infections?
a) Adherence to the host cells is mediated by the bacterial proteins
b) The bacteria enter the host cell by releasing exotoxin
c) Inhibited by beta-lactam antibiotics
d) All of the above

15) Which of the following is the drug of choice for Ureaplasma urealyticum infections?
a) Penicillin
b) Tetracyclines
c) Cephalosporins
d) Imipenem

16) Which of the following virulence factor is present in Mycoplasma pneumoniae, also known as Community-acquired distress syndrome toxin?
a) Endotoxin
b) Capsule
c) Lipid
d) Exotoxin

17) Mycoplasma pneumoniae can cause extrapulmonary infections and can infect mucous membranes and cutaneous membranes. Symptoms usually include rashes, soreness, and inflammation of these membranes.
Name the commonly used term for this type of infection?
a) Sporotrichosis
b) Epiglottitis
c) Mucositis
d) Cellulitis

18) What are the different types of infections commonly associated with M. genitalium?
Select all the correct answers:
a) Nongonococcal urethritis in men and women 
b) Pelvic inflammatory disease in women
c) Trachoma
d) Gonorrhoea
e) Infertility in women

19) Due to the lack of cell wall, the drug penicillin is not effective against M. genitalium, and the bacteria have shown high resistance to azithromycin and other macrolides. 
Name the drug used for the treatment of infections associated with M.genitalium
a) Moxifloxacin
b) Ceftriaxone
c) Acyclovir
d) Retrovir

20) Which of the following pathogen is Not the major cause of bronchitis?
a) Bordetella pertussis
b) Chlamydia trachomatis
c) Mycoplasma pneumniae
d) Respiratory syncytial virus

21) Which of the following culture media is a selective media commonly used for the isolation of M. hominis
a) Chocolate agar media
b) Eaton's agar media
c) MacConkey agar
d) New York City (NYC) media

22) Which organism is more likely to cause extrapulmonary symptoms, such as skin rashes and joint pain?
a. Mycoplasma pneumoniae
b. Streptococcus pneumoniae
c. Both
d. Neither

23) What is the purpose of using a suitable transport medium for Mycoplasma specimens?
a. To enhance specimen coloration
b. To prevent drying and maintain specimen viability
c. To speed up specimen processing
d. To eliminate contamination

Multiple Choice Answers Review:
1)- a) Pneumonia, c) Urethritis. M. pneumoniae is one of the most common cause of lower respiratory tract infection primarily infectiong young adults. Microplasma spp is found as a normal flora of urethra of urinary tract system, M. hominis can cause urethritis (nongonococcal urethritis) by sexual transmission.

2)- b) They appear as large in size in culture media. Mycoplasma spp. are cell wall deficient bacteria meaning they lack the rigid cell walls typically found in other bacterial species. They are among the smallest free-living organisms and the cultures grow relatively slowly compared to other bacteria.

3)- c) Tetracyclines
4)- c) It requires urea for its growth
5)- a) True
6)- c) Mycoplasma pneumoniae. It is one of the most common cause of lower respiratory tract infection primarily infectiong young adults.
7)- b) Mycoplasma hominis and c)Ureaplasma urealyticum
8)- d) Electron microscopy
9)- a) Streptococcus pneumoniae, c) Mycoplasma pneumoniae, d) Haemophilus influenzae
10)- c) Mycoplasma hominis
11)- a) Ureaplasma urealyticum
12)- b) 40 to 80 %
13)- c) 5 to 20
14)- a) Adherence to the host cells is mediated by the bacterial proteins
15)- b) Tetracyclines
16- d) Exotoxin
17- c) Mucositis
18- a), b) and e)
19- a)Moxifloxacin
20- b) Chlamydia trachomatis
21- d) New York City (NYC) medium. A transparent clear-to yellow medium containing lysed horse blood, horse plasma, yeast dialysate, and antimicrobials is primarily used for the growth of genital mycoplasmas.
22- a) Mycoplasma pneumoniae. Mycoplasma infections can manifest with extrapulmonary symptoms, including skin rashes, joint pain, and gastrointestinal symptoms.
23- b)To prevent drying and maintain specimen viability