MCQ on Haemophilus spp & Bordetella spp - gram negative coccobacilli bacteria


                                Multiple Choice Question on Haemophilus & Bordetella

1) Which of these small, gram-negative coccobacillus are clinically important human pathogens?
a) Haemophilus influenzae
b) Bordetella pertussis
c) Haemophilus parainfluenzae
d) Streptococcus pyogenes
e) Brucella melitensis

2) Name the two common bacteria that resides as normal flora in the upper respiratory tract of human which is also commonly isolated respiratory pathogens
a) Haemophilus influenzae
b) Mycoplasma pneumoniae
c) SARS CoV-2
d) Aspergillus fumigatus
e)Streptococcus pneumoniae

3) Which of the following gram-negative coccobacillus require both the X (hemin) and V (NAD) factors for its growth?
a) Neisseria gonorrhoeae
b) Bordetella pertussis
c) Streptococcus pyogenes
d) Haemophilus influenzae

4) Which of the following are NOT the virulence factors responsible for the pathogenicity of Bordetella pertussis that causes “whooping cough” disease?
a) An Endotoxin
b) A fimbriae and hemagglutinin
c) A pertussis toxin
d) A tracheal cytotoxin

5) Which of the following bacteria is an obligate aerobe, a highly contagious pathogen that may cause serious respiratory infections in young children?
a) Haemophilus ducreyi
b) Francisella tularensis
c) Bordetella pertussis
d) Haemophilus parainfluenzae

6) B. pertussis is only found in the human respiratory tract?
a) True
b) False

7) Which of the following agar is the selective culture media for the proper growth of B.pertussis?
a) Sheep blood agar
b) Charcoal horse blood agar
c) Potato dextrose agar
d) Mannitol salt agar
e) Chocolate agar

8) Name the highly contagious coccobacillus that is naturally found in animals such as squirrels, mice, and rabbits?
a) Francisella tularensis
b) Haemophilus influenzae type b
c) Histoplasma capsulatum
d) Bordetella parapertussis

9) All of the following are the major virulence factors present in H. influenzae, Except?
a) Capsule
b) Neuraminidase
c) IgA protease
d) Exotoxins
e) Lipid A

10) Which of the following are Not the general characteristics of Haemophilus ducreyi?
a) Gram-negative coccobacillus
b) It grows well on standard chocolate agar
c) It requires the X factor but not the V factor
d) It is susceptible to erythromycin

11) Name the antibiotics group which is NOT a commonly used drug for the treatment of infections caused by Haemophilus influenzae?
a) Third-generation cephalosporins
b) Aminopenicillins with a beta-lactamase inhibitor
c) Chloramphenicol with ampicillin
d) Amoxicillin with penicillin

12) What is a ' Quellung reaction '?
a) The capsule detection test
b) The serological antibody detection test
c) Direct antigen detection test
d) The bacterial motility test

13) The preventive measure for Bordetella pertussis infection is the vaccination method, the pertussis vaccine is usually administered in combination with toxoids of Diphtheria and tetanus (DTaP) that is recommended by WHO for children, preteens, pregnant women, and adults who have never received it.
What doses of the vaccine are usually recommended for children under six years?
a) Two doses of vaccine
b) Three doses of vaccine
c) Five doses of vaccine
d) One dose of vaccine

14) ........................................... is the causative agent of the chancroid, one of the most common sexually transmitted diseases and is characterized by painful lesions and genital ulcers?
a) Neisseria gonorrohoeae
b) Haemophilus haemolyticus
c) Treponema pallidum
d) Haemophilus ducreyi

15) Which of the following do not prove to be helpful for the treatment of the disease "whooping cough"?
a) Cough syrups and expectorants
b) DPT vaccine
c) Macrolides
d) None of the above

16) H. parainfluenzae can grow on blood agar and requires which of the following factor for proper growth in the clinical laboratory?
a) X (hemin factor)
b) V (NAD+ factor)
c) X and V factor
d) None of the above

17) What is the most common infection associated with type b H. influenzae?
a) Conjunctivitis
b) Genital chancre
c) Arthritis
d) Meningitis

18) Haemophilus influenzae are mainly categorized into serotype and nonserotype, which of the following component is present in the serotype H.influenzae?
a) Exotoxin
b) Flagella
c) Capsule
d) Teichoic acid

19) Haemophilus influenzae type b vaccine (Hib) is the preventive measure for the control of the infections caused by the bacteria, the Hib vaccine should usually be complete at which of the following age group of the children?
a) 1 to 5 year old
b) 2 months to 15 months old
c) 5 to 10 year old
d) 6 months to 5 years old

20) The cause of sore throat and difficulty breathing in young children is usually due to type b H.influenzae infection, what is it called?
a) Epiglottitis and cellulitis
b) Otitis media
c) Brazilian purpuric fever
d) Lassa fever

Multiple Choice Answers:
1- a), b), c), and e) are correct
Option dStreptococcus pyogenes is a gram positive coccus
2-c) Haemophilus influenzae and (e) Streptococcus pneumoniae
3-d) H. influenzae
4-a) An Endotoxin
5-c) B. pertussis
6-a) True
7-b) Charcoal horse blood agar (Regan-Lowe agar)
8-a)Francisella tularensis
9-d) Exotoxins
10-b) It grows well on standard chocolate agar
11-d) Amoxicillin with penicillin
12-a) The capsule detection test
13-c) Five doses of vaccine
14-d) Haemophilus ducreyi
15-a) Cough syrups and expectorants
16-b) V or NAD+factor
17-d) meningitis
18-c) Capsule
19-b) 2 months to 15 months old
20-a) Epiglottitis and cellulitis