MCQ on Neglected Tropical Diseases - Medical microbiology

                                           MCQ on Neglected Tropical Diseases 

                                             Image 1: Woman with lymphatic Filariasis

1. Onchocerciasis, a disease that is prevalent in West Africa is also known as....................................
a) Yellow fever
b) River blindness     
c) Filariasis
d) Leishmaniasis

2. Name the disease that has all of the following characteristics.
i) Most common parasitic disease in the world
ii) Prevalent in people living in rural areas 
iii) >400 million people get infected each year throughout the world
a) Rabies
b) Zika 
c) Echinococcosis
d) Ascariasis    

3. Female Genital Schistosomiasis (FGS) is one of the major neglected tropical disease affecting millions of girls and young women in Africa. 
Select all the correct statements about the disease?
a) The egg of the parasite is transferred through contaminated river water and gets deposited in the genital tract
b) It is a sexually transmitted viral disease 
c) FGS complications may lead to increase risk of HIV infection
d) If diagnosed early, the infection can be treated with regular treatment with Praziquantel

4. Which of the following NTDs are prevalent in tropical regions of the world with poor sanitations practices and people living in impoverished communities? 
Select all the correct answers
a) Trichuriasis (Whipworm disease)
b) Scabies
c) Hookworm disease
d) Salmonellosis

5. Select all the correct statements regarding Lymphatic filariasis 
a) It is a mosquito borne parasitic infection
b) Symptoms first appear from early age between 5-10 year       
c) Causes lymphangitis and lymphandenitis
d) The appropriate specimen is thick and thin blood smear for the identification of the parasite

6. Which of the following Mycobacterium spp causes skin infection also known as 'Buruli ulcer' and is one of the most common neglected tropical disease mainly found in rural parts of Africa and Australia?
a) Mycobacterium tuberculosis
b) Mycobacterium leprae
c) Mycobacterium ulcerans     
d) Mycobacterium marinum

7. 'Fascioliasis' is one of the common neglected tropical disease, it is caused by 'liver fluke'/ sheep liver fluke which is a.................................. 
a) Parasite     
b) Bacteria
c) Fungi
d) Toxins

8. Which of the following parasitic neglected tropical disease is transmitted to humans via the vector sandflies?
a) Filariasis 
b) Malaria
c) Leishmaniasis
d) African Trypanosomiasis

9. Dengue and Chikungunya viral infections are the most common NTDs prevalent in many parts of the world, these two infections are transmitted to humans by the bite of which of the following vector?
a) Anopheles spp mosquitoes      
b) Aedes aegypti mosquitoes  
c) Tsetse fly
d) Hyalomma spp ticks

10. 'Chagas' disease or American trypanosomiasis is transmitted by the bite of 'kissing bug' (insect) vector which transfers the parasite to humans.
Name the possible parasite?
a) Toxoplasma gondii
b) Plasmodium vivax
c) Balantidium coli
d) Trypanosoma cruzi

Answers with Explanation:
1. b) River blindness  

2.Correct answer is d) Ascariasis. 
a) Rabies and b) Zika are viral infections, Echinococcosis is a parasitic disease, the prevalence rate for the disease is much lower than Ascariasis.

3.Correct answer is  a), b), and c)
b) It is a sexually transmitted viral disease is Incorrect because it is not a sexually transmitted disease.
4. d) Salmonellosis is a bacterial infection and not a Neglected tropical disease.

5.Correct answer is  a), c), and d). 
b) Symptoms first appear from early age between 5-10 year  is Incorrect, symptoms appear when an individual reaches puberty age ( 15-16)

6.Correct answer is  c) Mycobacterium ulcerans

7.Correct answer is  a) Parasite
Fasciola hepatica is a parasite that mainly resides in sheep and cattle, when transmitted to humans can cause intestine and liver infections. 
8.Correct answer is  c) Leishmaniasis. It is transmitted to humans by sandflies.
a) Filariasis and b) Malaria is transmitted to humans by the bite of the mosquitoes. d) African Trypanosomiasis is transmitted by Tsetse fly.

9.Correct answer is  b) Aedes aegypti mosquitoes
a) Anopheles spp mosquitoes causes Malaria (a parasitic infection), c) Tsetse fly causes Leishmaniasis (a parasitic infection), and d) Hyalomma spp ticks can cause viral disease and Rickettsia (bacterial infection) 

10.Correct answer is d) Trypanosoma cruzi, a parasite that can transmit through bite of insect vector.
a) Toxoplasma gondii, a parasite transmitted to humans through ingestion of contaminated water and food (meat). b) Plasmodium vivax, a parasite transmitted to humans by the bite of mosquitoes.
c) Balantidium coli, a protozoa transmitted to humans through ingestion of contaminated water and food.