MCQ on Microorganisms Associated With Cancer

1. Epstein Barr virus is most commonly associated with all of the following types of cancers, Except?
a) Burkitt's lymphoma
b) Hodgkin's disease
c) Kaposi's sarcoma         
d) Nasopharyngeal carcinoma

2. All of the following regarding the Rous sarcoma virus is correct, Except?
a) The first described oncogenic RNA virus
b) It is used as a DNA tumor virus
c) First identified from a tumor in chickens
d) It consists of the extra oncogene causing sarcoma 

3A 47 year old woman suffering from gastritis for more than 3 years and has been taking medication for gastritis, pain killers for episodes of abdominal pain. Since the diagnosis she lost more than 15 pounds and had a problem gaining weight, the symptoms got worse even with more diet restrictions. The blood and feces samples for laboratory examination were submitted and endoscopy was also performed. Stomach ulcer was confirmed from the tests, which of the following microbe could be the possible pathogen that has been associated with gastrointestinal cancer mostly in developing countries?
a) Hepatitis A
b) Human papillomavirus
c) Helicobacter pylori         
d) Enterococcus faecalis

4. Which of the following statement is NOT correct about the vaccination for Human papillomavirus that could help prevent cancer?
a) HPV vaccination is best recommended at ages of 11 to 13
b) It can protect both men and women from more than 5 types of cancers
c) Prevents from getting cervical cancer
d) In the USA it is given to people 19 and under    

5. Name the following microorganism that is most commonly isolated from skin associated with cancer, it is also a part of a normal skin flora
a) Herpesvirus
b) Merkel cell polyomavirus       
c) Epstein Barr virus
d) Hepatitis B and C

6. Which of the following is Not considered the common risk factors for increasing the chance of mutation in the gene and cancer in humans?
a) Tobacco uses
b) Ultraviolet sunrays
c) Frozen foods       
d) High alcohol consumption

7. Which of the following is the most common microorganism linked to the cases of cervical cancer worldwide?
a) Hepatitis C virus
b) Human immunodeficiency virus
c) Retrovirus
d) Human papillomavirus       

8. A 36 year old HIV-positive man comes to the hospital with enlarged lymph nodes around the groin area, the infected area is painless but itchy. Name the most common disease the patient could be infected with
a. Hodgkin disease       
b. Merkel cell carcinoma
c. Non-Hodgkin lymphoma

9. Which of the following could be the possible etiological agent associated with the above (8) question?
a) Herpesvirus             
b) Human papillomavirus
c) Poxvirus
d) Adenovirus

10. According to the Centers for Disease Control and Prevention which of the following microbe is associated with the leading cause of hepatocellular carcinoma in the USA and worldwide?
a) Helicobacter pylori
b) Hepatitis B and C        
c) Epstein Barr virus
d) Papillomavirus 16 and 18

11. Which of the following statements regarding the several studies based on the link between chronic oral infections and cancer is mostly Not correct?
a) Smoking have been found as the major risk factor
b) Mainly occurs in adulthood and older ages
c) Person infected with STD
d) Adenovirus is mainly associated with oral cancer   

12. Name the microorganism associated with an increased risk of Non-Hodgkin lymphoma and lymphocytic leukemia
a) Adenovirus
b) Polyomavirus
c) Human T- lymphotrophic virus- 1    
d) Simian virus 40

13. HeLa continuous cell lines which is widely used in laboratories is derived from which type of cancer cells that have known to contain Human papillomavirus?
a) Oral cancer cells
b) Cervical cancer cells      
c) Liver cancer cells
d) Lung cancer cells

14. All of the following DNA viruses are the possible oncogenic viruses, Except?
a) Human T cell leukemia virus      
b) Herpes simplex virus
c) Poxvirus
d) Hepatitis B and C virus

15. Name the most likely bacteria that have been linked to cancer in humans, select from the options below
a) Helicobacter pylori     
b) E. coli
c) Salmonella typhi       
d) Plasmodium falciparum

1. c)Kaposi's sarcoma 
2. d)It consists of the extra oncogene causing sarcoma 
3. c)Helicobacter pylori    
4. d)In the USA it is given to people 19 and under    
5. b)
6. c)Frozen foods 
7. d)Human papillomavirus  
8. a)Hodgkin disease   
9. a)
10. b)Hepatitis B and C
11. d)
12. c)
13. b)
14. a)
15. a) and c)

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