BIOCHEMISTRY, BIOMEDICINE & PHARMACEUTICS

Multiple Choice Question on Coronavirus 1) The first case of coronavirus that causes severe acute respiratory syndrome ( SARS-CoV ) was first identified in Asia in 2003. Which of the following country has the highest number of confirmed death cases from the virus? a. China b. Brazil c. USA d. Italy 2) When was the first case of the COVID-19 ( coronavirus disease-19 ) infection reported in the USA? Select from the options below a. 2003 b. 2013 c. 2019 d. 2020 3) Which of the following virus may not show flu-like symptoms in humans? a. Coronavirus b. Rhinovirus c. Rotavirus d. Influenza virus 4) Which of the following statement is incorrect about the important characteristics/properties of Coronavirus? a. Non-Enveloped RNA virus b. Enveloped RNA virus c. Distributed around the world d. Transmitted from person to person 5) Coronavirus can cause gastroenteritis in animals. True or False? a. True b. False 6) Which of the following group of people have a high ...

Glutamate and Glutamine Metabolism: Glutamate and Glutamine are nutritionally non-essential amino acids that are the building block of proteins and, the precursor for the synthesis of other nonessential amino acids, urea, and neurotransmitters. Glutamine also serves as a co-substrate for the formation of asparagine. The glutamate and glutamine synthesis reaction uniquely incorporates free ammonium ions and is important for ammonia metabolism and detoxification. The metabolic pathway for the synthesis of glutamate and glutamine involves :   i) Conversion of alpha-ketoglutarate to glutamate by enzyme glutamate dehydrogenase, an NADPH requiring an enzyme that incorporates free ammonia into alpha-keto-glutarate.  ii) Conversion of glutamate to glutamine is catalyzed by Glutamine synthetase which incorporates ammonium ion and utilizes ATP as energy. Metabolism of Glutamine and Glutamine  Fates of Glutamate  Metabolism of Serine and Glycine Overvie...

                         Multiple Choice Questions on Bile Acid Metabolism 1) Most of the plasma proteins are synthesized in the liver.  Which of the following plasma protein is not synthesized in the liver? a) Albumin b) Transferrin c) Ceruloplasmin d) von Willebrand factor 2) Which of the following is not the metabolic function of the liver? a) Synthesis and assembly of chylomicrons b) Synthesis and secretion of bile acids c) Synthesis and breakdown of glycogen d) Gluconeogenesis 3) Bile acids are conjugated to amino acids or taurine to form bile salts.  Which of the following amino acid is utilized for conjugation reaction? a) Alanine b) Glycine c)Valine d)Leucine 4) Cholic acid and Chenodeoxycholic acid are the primary bile acid synthesized in the liver.  The bile acid is converted into secondary bile acids (eg. deoxycholic acid) by ............................................................. a) E...

                   MCQs  on  Antibiotic resistant microorganisms 1.Overuse of sanitizer may induce resistance in microorganisms a) TRUE    b) FALSE 2. Which of the following respiratory pathogens are the common worldwide antibiotic resistance bacteria? a) Staphylococcus aeruginosa  and Neisseria gonorrhoea b) Staphylococcus aureus and Haemophilus influenzae c) Staphylococcus aureus  and Mycobacterium tuberculosis d) Streptococcus pneumoniae and Mycobacterium tuberculosis      3. Which of the following gram positive bacteria have become a threat and is considered a global pandemic in antibiotic resistivity? a) Methicillin resistant Staphylococcus aureus (MRSA)     b) Mycobacterium tuberculosis c) Pseudomonas aeruginosa d) Candida albicans 4. Which of the following group of gram negative bacteria previously susceptible to carbapenem have become resistant (treatment of last resort) ...

                         MCQs on Glycogen Synthesis and Breakdown 1) Which of the following is false about glycogen molecules? a) Glycogen is a polysaccharide b) Glycogen is a polymer of beta-D-Glucose c) Glycogen consists of α ( 1-4 ) and α ( 1-6 ) glycosidic linkage d) Glycogen have are a helical structure with branching. 2) Which of the following organs does not have glycogen storage? a) Liver b) Muscle c) Intestine d) Erythrocytes 3) Which of the following enzyme is responsible for glycogen breakdown? a) Glycogen phosphorylase b) Glycogen phosphatase c) Glycogen hydrolase d) Glycogen phospho beta-glucosidase 4) Liver glycogen contributes to the maintenance of glucose but not muscle glycogen.  Which of the following enzyme is absent in muscle? a) Glycogen phosphorylase b) Hexokinase c) Glucose-6-phosphatase d) Debranching enzyme 5) Which of the enzyme is responsible for the hydrolysis ...